santa cruz biotechnology, inc.
goat polyclonal IgG, 200 µg/ml epitope mapping within the leucine-zipper domain of C/EBP γ of human origin recommended for detection of C/EBP γ of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian blocking peptide, sc-7659 P TransCruz reagent for Gel Supershift and ChIP applications, sc-7659 X, 200 µg/0.1 ml
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Species
Gene Name
Gene ID
Chromosome Location
Isoform (mRNA) Accession #
Protein Accession #
OMIM™ Number
Human
CEBPG
1054
19q13.11
NM_001806
P53567
138972
Mouse
Cebpg
12611
7 B1
P53568
N/A
C/EBP γ Background Information The transcription factor C/EBP å (CCAAT-enhancer binding protein) is a heat-stable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP å regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP å uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP å appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP ∫, C/EBP ©, C/EBP ∂ and C/EBP e, all of which exhibit similar DNA-binding specificities and affinities to C/EBP å. Furthermore, C/EBP ∫ and C/EBP ∂ readily form heterodimers both with each other as well as with C/EBP å.
C/EBP γ (E-19) Product Citations
See how others have used C/EBP γ (E-19): sc-7659 antibody and or C/EBP γ (E-19) antibody conjugates.
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