epitope mapping near the C-terminus of Adenosine A1-R of human origin
recommended for detection of Adenosine A1-R of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
Adenosine A1-R Background Information Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNFå and blocks the endotoxin CD14 receptor signal transduction pathway.
Adenosine A1-R (C-19) Product Citations
See how others have used Adenosine A1-R (C-19): sc-7500 antibody and or Adenosine A1-R (C-19) antibody conjugates.