Date published: 2026-7-18

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PARP Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PARP Antibodies for advanced research in cellular biology. PARP Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Poly(ADP-ribose) polymerase (PARP) plays a crucial role in DNA repair processes and cellular responses to stress. By detecting and repairing single-strand breaks in DNA, PARP maintains genomic stability and prevents cell death. PARP's involvement in various cellular functions makes it a significant target in cancer research and therapeutic development. Researchers worldwide rely on PARP monoclonal antibodies to investigate DNA repair pathways and their connection to disease progression. Understanding PARP's molecular mechanisms has led to breakthrough discoveries in cancer treatment strategies. PARP monoclonal antibodies enable precise detection and analysis of DNA repair processes. Santa Cruz Biotechnology monoclonal antibodies for PARP research continue to advance scientific understanding of cellular repair mechanisms and support the development of innovative therapeutic approaches.

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PARP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PARP1 Antibody (F-2)

sc-8007mouse IgG2a κ764-1014 (h)WB, IP, IF, IHC(P), ELISAh
890
(93)

PARP1 Antibody (B-10)

sc-74470mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
71
(17)

PARP1 Antibody (D-1)

sc-365315mouse IgG1 κ1-27 (m)WB, IP, IF, ELISAm, r, h
27
(10)

PARP1 Antibody (E-8)

sc-74469mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
24
(8)

PARP1 Antibody (5A5)

sc-56197mouse IgG1(h)WB, IP, IFm, r, h
32
(9)

PARP1 Antibody (42)

sc-136208mouse IgG122-219 (h)WB, IP, IFm, r, h
22
(9)

PARP1 Antibody (194C1439)

sc-56196mouse IgG2bcleavage site 214/215 (h)WB, IPm, r, h
128
(27)

PARP-2 Antibody (F-8)

sc-393343mouse IgM κ105-148 (h)WB, IP, IF, ELISAm, r, h
1
(5)

PARP-2 Antibody (F-3)

sc-393310mouse IgG2a κ103-138 (h)WB, IP, IF, ELISAm, r, h
6
(3)

PARP-3 Antibody (B-7)

sc-390771mouse IgG2a κ139-219 (h)WB, IP, IF, ELISAm, r, h
5
(5)

PARP-3 Antibody (C-1)

sc-390758mouse IgG1 κ139-219 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PARP-4 Antibody (B-11)

sc-515898mouse IgG1 κ653-885 (h)WB, IP, IF, ELISAm, r, h

new

(2)

PARP-10 Antibody (5H11)

sc-53858rat IgG1(h)WB, IP, IFm, r, h
2
(2)

PARP-10 Antibody (6D643)

sc-71851rat IgG1(h)WB, IP, IFm, r, h
1
(1)

PARP-14 Antibody (C-1)

sc-377150mouse IgG1 κ291-358 (h)WB, IP, IF, ELISAm, r, h
12
(4)

PARP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PARP1 siRNA (h)

sc-29437hGene SilencingN/A
43
(3)

PARP1 shRNA Plasmid (h)

sc-29437-SHhGene SilencingPuromycin
43
(3)

PARP1 shRNA (h) Lentiviral Particles

sc-29437-VhGene SilencingPuromycin
43
(3)

PARP1 siRNA (m)

sc-29438mGene SilencingN/A
9
(0)

PARP1 shRNA Plasmid (m)

sc-29438-SHmGene SilencingPuromycin
9
(0)

PARP1 shRNA (m) Lentiviral Particles

sc-29438-VmGene SilencingPuromycin
9
(0)

PARP-2 siRNA (h)

sc-106356hGene SilencingN/A
1
(0)

PARP-2 shRNA Plasmid (h)

sc-106356-SHhGene SilencingPuromycin
1
(0)

PARP-2 shRNA (h) Lentiviral Particles

sc-106356-VhGene SilencingPuromycin
1
(0)

PARP-2 siRNA (m)

sc-152028mGene SilencingN/A
4
(0)

PARP-2 shRNA Plasmid (m)

sc-152028-SHmGene SilencingPuromycin
4
(0)

PARP-2 shRNA (m) Lentiviral Particles

sc-152028-VmGene SilencingPuromycin
4
(0)

PARP-3 siRNA (h)

sc-106357hGene SilencingN/A
1
(0)

PARP-3 shRNA Plasmid (h)

sc-106357-SHhGene SilencingPuromycin
1
(0)

PARP-3 shRNA (h) Lentiviral Particles

sc-106357-VhGene SilencingPuromycin
1
(0)

PARP-3 siRNA (m)

sc-152029mGene SilencingN/A0
(0)

PARP-3 shRNA Plasmid (m)

sc-152029-SHmGene SilencingPuromycin0
(0)

PARP-3 shRNA (m) Lentiviral Particles

sc-152029-VmGene SilencingPuromycin0
(0)

PARP-4 siRNA (h)

sc-61299hGene SilencingN/A
1
(0)

PARP-4 shRNA Plasmid (h)

sc-61299-SHhGene SilencingPuromycin
1
(0)

PARP-4 shRNA (h) Lentiviral Particles

sc-61299-VhGene SilencingPuromycin
1
(0)

PARP-6 siRNA (h)

sc-76062hGene SilencingN/A0
(0)

PARP-6 shRNA Plasmid (h)

sc-76062-SHhGene SilencingPuromycin0
(0)

PARP-6 shRNA (h) Lentiviral Particles

sc-76062-VhGene SilencingPuromycin0
(0)

PARP-6 siRNA (m)

sc-76063mGene SilencingN/A0
(0)

PARP-6 shRNA Plasmid (m)

sc-76063-SHmGene SilencingPuromycin0
(0)

PARP-6 shRNA (m) Lentiviral Particles

sc-76063-VmGene SilencingPuromycin0
(0)

PARP-7 siRNA (h)

sc-76064hGene SilencingN/A0
(0)

PARP-7 shRNA Plasmid (h)

sc-76064-SHhGene SilencingPuromycin0
(0)

PARP-7 shRNA (h) Lentiviral Particles

sc-76064-VhGene SilencingPuromycin0
(0)

PARP-7 siRNA (m)

sc-76065mGene SilencingN/A0
(0)

PARP-7 shRNA Plasmid (m)

sc-76065-SHmGene SilencingPuromycin0
(0)

PARP-7 shRNA (m) Lentiviral Particles

sc-76065-VmGene SilencingPuromycin0
(0)

PARP-8 siRNA (h)

sc-76066hGene SilencingN/A0
(0)

PARP-8 shRNA Plasmid (h)

sc-76066-SHhGene SilencingPuromycin0
(0)

PARP-8 shRNA (h) Lentiviral Particles

sc-76066-VhGene SilencingPuromycin0
(0)

PARP-8 siRNA (m)

sc-76067mGene SilencingN/A0
(0)

PARP-8 shRNA Plasmid (m)

sc-76067-SHmGene SilencingPuromycin0
(0)

PARP-8 shRNA (m) Lentiviral Particles

sc-76067-VmGene SilencingPuromycin0
(0)

PARP-9 siRNA (h)

sc-76068hGene SilencingN/A0
(0)

PARP-9 shRNA Plasmid (h)

sc-76068-SHhGene SilencingPuromycin0
(0)

PARP-9 shRNA (h) Lentiviral Particles

sc-76068-VhGene SilencingPuromycin0
(0)

PARP-9 siRNA (m)

sc-76069mGene SilencingN/A0
(0)

PARP-9 shRNA Plasmid (m)

sc-76069-SHmGene SilencingPuromycin0
(0)

PARP-9 shRNA (m) Lentiviral Particles

sc-76069-VmGene SilencingPuromycin0
(0)

PARP-10 siRNA (h)

sc-63306hGene SilencingN/A0
(0)

PARP-10 shRNA Plasmid (h)

sc-63306-SHhGene SilencingPuromycin0
(0)

PARP-10 shRNA (h) Lentiviral Particles

sc-63306-VhGene SilencingPuromycin0
(0)

PARP-11 siRNA (h)

sc-76052hGene SilencingN/A0
(0)

PARP-11 shRNA Plasmid (h)

sc-76052-SHhGene SilencingPuromycin0
(0)

PARP-11 shRNA (h) Lentiviral Particles

sc-76052-VhGene SilencingPuromycin0
(0)

PARP-11 siRNA (m)

sc-76053mGene SilencingN/A0
(0)

PARP-11 shRNA Plasmid (m)

sc-76053-SHmGene SilencingPuromycin0
(0)

PARP-11 shRNA (m) Lentiviral Particles

sc-76053-VmGene SilencingPuromycin0
(0)

PARP-12 siRNA (h)

sc-76054hGene SilencingN/A0
(0)

PARP-12 shRNA Plasmid (h)

sc-76054-SHhGene SilencingPuromycin0
(0)

PARP-12 shRNA (h) Lentiviral Particles

sc-76054-VhGene SilencingPuromycin0
(0)

PARP-12 siRNA (m)

sc-76055mGene SilencingN/A0
(0)

PARP-12 shRNA Plasmid (m)

sc-76055-SHmGene SilencingPuromycin0
(0)

PARP-12 shRNA (m) Lentiviral Particles

sc-76055-VmGene SilencingPuromycin0
(0)

PARP-14 siRNA (h)

sc-76056hGene SilencingN/A0
(0)

PARP-14 shRNA Plasmid (h)

sc-76056-SHhGene SilencingPuromycin0
(0)

PARP-14 shRNA (h) Lentiviral Particles

sc-76056-VhGene SilencingPuromycin0
(0)

PARP-14 siRNA (m)

sc-76057mGene SilencingN/A0
(0)

PARP-14 shRNA Plasmid (m)

sc-76057-SHmGene SilencingPuromycin0
(0)

PARP-14 shRNA (m) Lentiviral Particles

sc-76057-VmGene SilencingPuromycin0
(0)

PARP-15 siRNA (h)

sc-76058hGene SilencingN/A0
(0)

PARP-15 shRNA Plasmid (h)

sc-76058-SHhGene SilencingPuromycin0
(0)

PARP-15 shRNA (h) Lentiviral Particles

sc-76058-VhGene SilencingPuromycin0
(0)

PARP-16 siRNA (h)

sc-76060hGene SilencingN/A0
(0)

PARP-16 shRNA Plasmid (h)

sc-76060-SHhGene SilencingPuromycin0
(0)

PARP-16 shRNA (h) Lentiviral Particles

sc-76060-VhGene SilencingPuromycin0
(0)

PARP-16 siRNA (m)

sc-76061mGene SilencingN/A0
(0)

PARP-16 shRNA Plasmid (m)

sc-76061-SHmGene SilencingPuromycin0
(0)

PARP-16 shRNA (m) Lentiviral Particles

sc-76061-VmGene SilencingPuromycin0
(0)

PARP CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PARP1 CRISPR/Cas9 KO Plasmid (h)

sc-400046Gene Knockouth0
(4)

PARP1 HDR Plasmid (h)

sc-400046-HDRHomology Directed Repairh0
(4)

PARP1 CRISPR/Cas9 KO Plasmid (m)

sc-419018Gene Knockoutm0
(0)

PARP1 HDR Plasmid (m)

sc-419018-HDRHomology Directed Repairm0
(0)

PARP-2 CRISPR/Cas9 KO Plasmid (h2)

sc-402224-KO-2Gene Knockouth0
(0)

PARP-2 HDR Plasmid (h2)

sc-402224-HDR-2Homology Directed Repairh0
(0)

PARP-2 CRISPR/Cas9 KO Plasmid (m)

sc-419019Gene Knockoutm0
(0)

PARP-2 HDR Plasmid (m)

sc-419019-HDRHomology Directed Repairm0
(0)

PARP-4 CRISPR/Cas9 KO Plasmid (h)

sc-406615Gene Knockouth0
(0)

PARP-6 CRISPR/Cas9 KO Plasmid (h)

sc-406698Gene Knockouth0
(0)

PARP-6 HDR Plasmid (h)

sc-406698-HDRHomology Directed Repairh0
(0)

PARP-7 CRISPR/Cas9 KO Plasmid (h)

sc-407777Gene Knockouth0
(0)

PARP-7 HDR Plasmid (h)

sc-407777-HDRHomology Directed Repairh0
(0)

PARP-9 CRISPR/Cas9 KO Plasmid (h)

sc-413492Gene Knockouth0
(0)

PARP-9 HDR Plasmid (h)

sc-413492-HDRHomology Directed Repairh0
(0)

PARP-10 CRISPR/Cas9 KO Plasmid (h)

sc-406703Gene Knockouth0
(0)

PARP-10 HDR Plasmid (h)

sc-406703-HDRHomology Directed Repairh0
(0)

PARP-10 CRISPR/Cas9 KO Plasmid (m)

sc-437160Gene Knockoutm0
(0)

PARP-11 CRISPR/Cas9 KO Plasmid (h)

sc-406676Gene Knockouth0
(0)

PARP-11 HDR Plasmid (h)

sc-406676-HDRHomology Directed Repairh0
(0)

PARP-12 CRISPR/Cas9 KO Plasmid (h)

sc-404566Gene Knockouth0
(0)

PARP-12 HDR Plasmid (h)

sc-404566-HDRHomology Directed Repairh0
(0)

PARP-14 CRISPR/Cas9 KO Plasmid (h2)

sc-402812-KO-2Gene Knockouthuman0
(0)

PARP-14 HDR Plasmid (h2)

sc-402812-HDR-2Homology Directed Repairhuman0
(0)

PARP-15 CRISPR/Cas9 KO Plasmid (h)

sc-414885Gene Knockouth0
(0)

PARP-15 HDR Plasmid (h)

sc-414885-HDRHomology Directed Repairh0
(0)

PARP-16 CRISPR/Cas9 KO Plasmid (h)

sc-408242Gene Knockouth0
(0)

PARP-16 HDR Plasmid (h)

sc-408242-HDRHomology Directed Repairh0
(0)

PARP CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PARP1 Double Nickase Plasmid (h)

sc-400046-NICGene Knockouth0
(0)

PARP1 Double Nickase Plasmid (h2)

sc-400046-NIC-2Gene Knockouth0
(0)

PARP1 Double Nickase Plasmid (m)

sc-419018-NICGene Knockoutm0
(1)

PARP1 Double Nickase Plasmid (m2)

sc-419018-NIC-2Gene Knockoutm0
(1)

PARP-2 Double Nickase Plasmid (h)

sc-402224-NICGene Knockouth0
(0)

PARP-2 Double Nickase Plasmid (h2)

sc-402224-NIC-2Gene Knockouth0
(0)

PARP-2 Double Nickase Plasmid (m)

sc-419019-NICGene Knockoutm0
(0)

PARP-7 Double Nickase Plasmid (h)

sc-407777-NICGene Knockouth0
(0)

PARP-7 Double Nickase Plasmid (h2)

sc-407777-NIC-2Gene Knockouth0
(0)

PARP-7 Double Nickase Plasmid (m)

sc-430288-NICGene Knockoutm0
(0)

PARP-9 Double Nickase Plasmid (h)

sc-413492-NICGene Knockouth0
(0)

PARP-9 Double Nickase Plasmid (h2)

sc-413492-NIC-2Gene Knockouth0
(0)

PARP-9 Double Nickase Plasmid (m)

sc-429785-NICGene Knockoutm0
(0)

PARP-9 Double Nickase Plasmid (m2)

sc-429785-NIC-2Gene Knockoutm0
(0)

PARP-12 Double Nickase Plasmid (h)

sc-404566-NICGene Knockouth0
(0)

PARP-12 Double Nickase Plasmid (h2)

sc-404566-NIC-2Gene Knockouth0
(0)

PARP-14 Double Nickase Plasmid (h)

sc-402812-NICGene Knockouth0
(0)

PARP-14 Double Nickase Plasmid (h2)

sc-402812-NIC-2Gene Knockouth0
(0)

PARP-15 Double Nickase Plasmid (h)

sc-414885-NICGene Knockouth0
(0)

PARP-15 Double Nickase Plasmid (h2)

sc-414885-NIC-2Gene Knockouth0
(0)

PARP CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

PARP1 CRISPR Activation Plasmid (h)

sc-400046-ACTGene Activationh0
(0)

PARP1 Lentiviral Activation Particles (h)

sc-400046-LACGene Activationh0
(0)

PARP1 CRISPR Activation Plasmid (m)

sc-419018-ACTGene Activationm0
(0)

PARP-2 CRISPR Activation Plasmid (h)

sc-402224-ACTGene Activationh0
(0)

PARP-2 CRISPR Activation Plasmid (h2)

sc-402224-ACT-2Gene Activationh0
(0)

PARP-7 CRISPR Activation Plasmid (h)

sc-407777-ACTGene Activationh0
(0)

PARP-7 CRISPR Activation Plasmid (h2)

sc-407777-ACT-2Gene Activationh0
(0)

PARP-10 CRISPR Activation Plasmid (m)

sc-437160-ACTGene Activationm0
(0)

PARP-10 CRISPR Activation Plasmid (m2)

sc-437160-ACT-2Gene Activationm0
(0)

PARP-10 Lentiviral Activation Particles (m)

sc-437160-LACGene Activationm0
(0)

PARP-14 CRISPR Activation Plasmid (h)

sc-402812-ACTGene Activationh0
(0)

PARP-14 CRISPR Activation Plasmid (h2)

sc-402812-ACT-2Gene Activationh0
(0)

PARP-14 Lentiviral Activation Particles (h)

sc-402812-LACGene Activationh0
(0)

PARP-14 Lentiviral Activation Particles (h2)

sc-402812-LAC-2Gene Activationh0
(0)

PARP-14 CRISPR Activation Plasmid (m)

sc-436859-ACTGene Activationm0
(0)

PARP-14 CRISPR Activation Plasmid (m2)

sc-436859-ACT-2Gene Activationm0
(0)