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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 1-298 representing full length Cdk2 of human origin
- recommended for detection of Cdk2 of mouse, rat and human origin by WB, IP, IF and ELISA; minimal cross-reactivity with other cyclin dependent kinases; also reactive with additional species, including equine, canine, bovine, porcine and avian
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Cdk2 Background Information In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.
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See how others have used Cdk2 (H-298): sc-748 antibody and or Cdk2 (H-298) antibody conjugates.
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Cdk2 (H-298)
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Cdk2 (H-298): sc-748. Western blot analysis of Cdk2 expression in NAMALWA whole cell lysate.
Cdk2 (H-298): sc-748. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and mouse Cdk2 transfected: sc-119146 (B) 293T whole cell lysates.
Cdk2 (H-298): sc-748. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and human Cdk2 transfected: sc-172351 (B) 293T whole cell lysates.
Cdk2 (H-298): sc-748. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and human Cdk2 transfected: sc-128295 (B) 293T whole cell lysates.
Cdk2 (H-298): sc-748. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
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