epitope corresponding to amino acids 199-345 of C/EBP β of human origin
recommended for detection of C/EBP β, C/EBP α, C/EBP δ and C/EBP ε of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including porcine
TransCruz reagent for Gel Supershift and ChIP applications, sc-746 X, 200 µg/0.1 ml
C/EBP β Background Information CCAAT-enhancer binding proteins (C/EBP) are basic region/leucine zipper (bZIP) transcription factors selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP ∫ is a member of the C/EBP transcription factor family. The C/EBP ∫ gene encodes several isoforms containing truncated transcription activation domains due to the alternative translational initiation at multipe AUG start sites. Initiation of translation at the in-frame AUGs forms 4 C/EBP ∫ isoforms. C/EBP ∫ is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein (LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP ∫ contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP ∫ gene that has direct implication for acute phase response in liver cells.
C/EBP β (Δ 198) Product Citations
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C/EBP β (Δ 198)
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C/EBP β (Δ 198): sc-746. Immunoperoxidase staining of formalin-fixed, paraffin-embedded mouse liver tissue showing nuclear staining of select cells.
C/EBP β (Δ 198): sc-746. Western blot analysis of human recombinant C/EBP β fusion protein.
C/EBP β (Δ 198): sc-746. Western blot analysis of C/EBP β expression in non-transfected 293T: sc-117752 (A), human C/EBP β transfected 293T: sc-176940 (B) and Jurkat (C) whole cell lysates.
