santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Signaling Intermediates » PDI Antibody / PDI Antibodies » PDI (C-2): sc-74551

PDI (C-2) Antibody: sc-74551

  |  Datasheet
  • mouse monoclonal IgG1, 200µg/ml
  • raised against amino acids 211-370 mapping near the N-terminus of PDI of human origin
  • recommended for detection of PDI of mouse, rat and human origin by WB, IP, IF and ELISA
 
Additional PDI Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human P4HB 5034 17q25.3 NM_000918 P07237
 176790
Mouse P4hb 18453 11 E2 P09103
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PDI (C-2) sc-74551 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PDI siRNA (h) sc-36201 10 µM $258
PDI siRNA (m) sc-36202 10 µM $258
PDI siRNA (h2) sc-44319 10 µM $258
PDI (h)-PR sc-36201-PR 10 µM $23
PDI (m)-PR sc-36202-PR 10 µM $23
PDI (h2)-PR sc-44319-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PDI shRNA Plasmid (h) sc-36201-SH 20 µg $520
PDI shRNA Plasmid (m) sc-36202-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PDI shRNA (h) Lentiviral Particles sc-36201-V 200 µl $625
PDI shRNA (m) Lentiviral Particles sc-36202-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
COLO 320DM Cell Lysate sc-2226 500 µg/200 µl $104
mouse liver extract sc-2256 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
PDI (h): 293 Lysate sc-111237 100µg/200µl $205
PDI (h2): 293T Lysate sc-113640 100µg/200µl $205
rat liver extract sc-2395 500 µg/200 µl $104

PDI Background Information
Oxidoreductase-protein disulfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disulfide exchange, mediates folding of newly synthesized proteins and functions as a molecular chaperone. PDI localizes to the lumen of the endoplasmic reticulum (ER), where in conjunction with folding-helper proteins, such as immunoglobulin heavy chain binding protein (BiP), mediates tertiary and quaternary protein-processing. Cell surface PDI induces sulfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regulating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins.

PDI (C-2) Product Citations
See how others have used PDI (C-2): sc-74551 antibody and or PDI (C-2) antibody conjugates.


1 total citations
Loading citations.
 
PDI (C-2)
Click on image to enlarge
sc-74551
PDI (C-2): sc-74551. Western blot analysis of PDI expression in COLO 320DM (A), Hep G2 (B), A-431 (C), TT (D) and c4 (E) whole cell lysates and mouse liver (F) and rat liver (G) tissue extracts.
sc-74551
PDI (C-2): sc-74551. Western blot analysis of PDI expression in non-transfected 293T: sc-117752 (A), human PDI transfected 293T: sc-113640 (B) and Hep G2 (C) whole cell lysates.
sc-74551
PDI (C-2): sc-74551. Western blot analysis of PDI expression in non-transfected 293T: sc-117752 (A), human PDI transfected 293T: sc-111237 (B) and Hep G2 (C) whole cell lysates.
sc-74551
PDI (C-2): sc-74551. Western blot analysis of PDI expression in non-transfected 293T: sc-117752 (A), mouse PDI transfected 293T: sc-125796 (B) and Hep G2 (C) whole cell lysates.
sc-74551
PDI (C-2): sc-74551. Western blot analysis of PDI expression in Hep G2 whole cell lysate.
sc-74551
PDI (C-2): sc-74551. Immunofluorescence staining of formalin-fixed Hep G2 cells showing nuclear localization.
Download
Datasheets
Get Adobe Acrobat Reader