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- mouse monoclonal IgG2a; 200 µg/ml
- raised against amino acids 1-447 representing full length NFκB p52 of human origin
- recommended for detection of NFκB p52 and p100 of mouse, rat and human origin by WB, IP, IF and FCM
- agarose conjugate for IP studies, sc-7386 AC, 500 µg/0.25 ml agarose
- TransCruz reagent for Gel Supershift and ChIP applications, sc-7386 X, 200 µg/0.1 ml
- phycoerythrin conjugate for intracellular FCM, sc-7386 PE, 100 tests
- Alexa Fluor® 405 (sc-7386 AF405), Alexa Fluor® 488 (sc-7386 AF488) and Alexa Fluor® 647 (sc-7386 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
NFKB2 |
4791 |
10q24.32 |
NM_002502 |
Q00653
|
164012 |
| Mouse |
Nfkb2 |
18034 |
19 C3 |
|
Q9WTK5
|
N/A |
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NFκB p52 Background Information
The NFkB transcription factor was originally identi-fied as a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino terminus of a precursor designated p105. A cDNA was isolated that encodes an alternative DNA binding subunit of NFkB. It is synthesized as a protein that is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFkB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.
| NFκB p52 (C-5) Product Citations |
See how others have used NFκB p52 (C-5): sc-7386 antibody and or NFκB p52 (C-5) antibody conjugates.
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NFκB p52 (C-5)
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NFκB p52 (C-5): sc-7386. Western blot analysis of NFκB p52 expression in HuT 78 whole cell lysate.
NFκB p52 (C-5) PE: sc-7386 PE. Intracellular FCM analysis of fixed and permeabilized HuT 76 cells. Black line histogram represents the isotype control, normal mouse IgG 2a: sc-2867. NFκB p52 (C-5) Alexa Fluor 488: sc-7386 AF488. Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal mouse IgG 2a: sc-3891. NFκB p52 (C-5) Alexa Fluor 647: sc-7386 AF647. Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal mouse IgG 2a: sc-24637. NFκB p52 (C-5) Alexa Fluor 488: sc-7386 AF488. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
NFκB p52 (C-5): sc-7386. Western blot analysis of NFκB p52 expression in non-transfected: sc-117752 (A) and mouse NFκB p52 transfected: sc-122026 (B) 293T whole cell lysates. |
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