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GABAA Rα3 (C-20) Antibody: sc-7352

 |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of GABAA Rα3 of human origin
  • recommended for detection of GABAA Rα3 and, to a lesser extent, GABAA Rα1, GABAA Rα2 and GABAA Rα5 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
  • blocking peptide, sc-7352 P
 
Additional GABA Receptor Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human GABRA3 2556 Xq28 NM_000808 P34903
305660
Mouse Gabra1 14394 11 A5 P62812
N/A
Mouse Gabra2 14395 5 C3.1 P26048
N/A
Mouse Gabra3 14396 X A7.3 P26049
N/A
Mouse Gabra5 110886 7 C Q8BHJ7
N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rα3 (C-20) sc-7352 200 µg/ml $279
GABAA Rα3 (C-20) P sc-7352 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rα3 siRNA (h) sc-42429 10 µM $258
GABAA Rα3 (h)-PR sc-42429-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rα3 shRNA Plasmid (h) sc-42429-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
GABAA Rα3 shRNA (h) Lentiviral Particles sc-42429-V 200 µl $625

GABAA Rα3 Background Information
GAD-65 and GAD-67, glutamate decarboxylases,, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rå1-6, GABAA R ∫1-3, GABAA R©1-3, GABAA R∂, GABAA Ré, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1å and GABAB R1∫. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.