Jun B Background Information The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B andJun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
Jun B (210) Product Citations
See how others have used Jun B (210): sc-73 antibody and or Jun B (210) antibody conjugates.
39 total citations
Loading citations.
Jun B (210)
Click on image to enlarge
Jun B (210): sc-73. Western blot analysis of Jun B expression in phorbol ester-induced NIH/3T3 (A), untreated KNRK (B) and phorbol ester-induced KNRK (C) nuclear extracts.
Jun B (210): sc-73. Western blot analysis of Jun B expression in non-transfected: sc-117752 (A) and mouse Jun B transfected: sc-121169 (B) 293T whole cell lysates.
Jun B (210): sc-73. Western blot analysis of Jun B expression in HeLa whole cell lysate.
Jun B (210): sc-73. Western blot analysis of Jun B expression in NIH/3T3 nuclear extract.
Jun B (210): sc-73. Western blot analysis of Jun B expression in non-transfected: sc-117752 (A) and human Jun B transfected: sc-170824 (B) 293T whole cell lysates.
