PML Antibody (5G191): sc-71910
- PML Antibody (5G191) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- recommended for detection of all isoforms of PML of human origin by WB, IP, IF and IHC(P)
- See PML (E-11): sc-377390 for PML antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PML Antibody (5G191) for WB and IHC(P) applications. These reagents are now offered in bundles with PML Antibody (5G191) (see ordering information below).
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SEE ALSO...
PML Antibody (5G191) is a mouse monoclonal IgG1 antibody that detects PML in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. PML, or promyelocytic leukemia protein, is a crucial zinc finger transcription factor that plays a significant role in regulating gene expression and maintaining cellular homeostasis. PML (5G191) antibody targets proteins primarily located in the nucleus, where PML is involved in various cellular processes, including apoptosis, cell cycle regulation, and DNA damage response. The proper localization of PML is essential for function, as PML forms nuclear bodies that are implicated in the regulation of transcription and the response to stress signals. Disruption of PML localization can lead to pathological conditions, including acute promyelocytic leukemia, where the PML/RARα fusion protein interferes with normal differentiation and promotes oncogenesis. Anti-PML antibody (5G191) enables researchers to gain insights into PML′s role in cellular processes and implications in cancer biology, making PML (5G191) monoclonal antibody a valuable research tool.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PML Antibody (5G191) | sc-71910 | 200 µg/ml | $316.00 | |||
PML Antibody (5G191): m-IgG Fc BP-HRP Bundle | sc-539423 | 200 µg Ab; 10 µg BP | $354.00 | |||
PML Antibody (5G191): m-IgG1 BP-HRP Bundle | sc-541482 | 200 µg Ab; 20 µg BP | $354.00 |