santa cruz biotechnology, inc.
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PI 3-kinase p110α (H-201) Antibody: sc-7174 |
| Datasheet |
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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 189-390 mapping near the N-terminus of PI 3-kinase p110α of human origin
- recommended for detection of PI 3-kinase p110α of mouse, rat, human and Xenopus origin by WB, IP, IF and ELISA
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
PIK3CA |
5290 |
3q26.32 |
NM_006218 |
P42336
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604370 |
| Mouse |
Pik3ca |
18706 |
3 A3 |
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P42337
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N/A |
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PI 3-kinase p110α Background Information
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85å and p85∫), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110å and p110∫ interact with p85å, and p110å has also been shown to interact with p85∫ in vitro. p110∂ expression is restricted to white blood cells. It has been shown to bind p85å and ∫, but it apparently does not phosphorylate these subunits. p110∂ seems to have the capacity to autophosphorylate. p110© does not interact with the p85 subunits. It has been shown to be activated by å and ∫© heterotrimeric G proteins.
| PI 3-kinase p110α (H-201) Product Citations |
See how others have used PI 3-kinase p110α (H-201): sc-7174 antibody and or PI 3-kinase p110α (H-201) antibody conjugates.
37 total citations Loading citations.
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PI 3-kinase p110α (H-201)
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PI 3-kinase p110α (H-201): sc-7174. Western blot analysis of PI 3-kinase p110α expression in Jurkat whole cell lysate.
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