 |
- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of CD13 of human origin
- recommended for detection of CD13 of mouse, rat and human origin by WB, IF, IHC(P) and ELISA; also reactive with additional species, including canine
- fluorescein conjugate for immunofluorescence, sc-6248 FITC, 200 µg/ml
- blocking peptide, sc-6995 P
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
ANPEP |
290 |
15q26.1 |
NM_001150 |
P15144
|
151530 |
| Mouse |
Anpep |
16790 |
7 D3 |
|
P97449
|
N/A |
| |
CD13 Background Information
CD13, or aminopeptidase N, is a type II transmembrane glycoprotein that is expressed on most cells of Myeloid origin, including monocytes, basophils, eosinophils, neutrophils and Myeloid leukemias. CD13 is also found on certain epithelial cells, fibroblasts and osteoclasts. CD13 acts as a zinc-binding metalloprotease that plays a role in digestion and may function in the inactivation of some regulatory peptides such as enkephalins. CD13 may play a role in the invasion of cancer cells by enhancing their invasive capacity and metastatic behavior. The activity of CD13 can be inactivated using specific inhibitors that evoke apoptosis of CD13-positive cancer cells. Basic fibroblast growth factor (bFGF) expression upregulates CD13 expression in human melanoma cells by activating both the Myeloid and the epithelial CD13 promoter.
| CD13 (C-17) Product Citations |
See how others have used CD13 (C-17): sc-6995 antibody and or CD13 (C-17) antibody conjugates.
2 total citations Loading citations.
|
| |
|
|
|
CD13 (C-17)
Click on image to enlarge
|
|
CD13 (C-17): sc-6995. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse kidney tissue showing membrane localization.
|
|
Download
|
|
