HIV-1 p24 Background Information Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. p24 is a viral protein encoded by the HIV-1 gag gene that provides structural elements of the virus along with p6, p7 and p17. Specifically, p24 makes up the viral capsid, p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix.
HIV-1 p24 (24-4)
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HIV-1 p24 (24-4): sc-69728. Western blot analysis of human recombinant HIV-1 gag (p17/p24/p15).
