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MYH11 Antibody (G-4): sc-6956

 |  Datasheet

(Based on data analysis)

  • MYH11 Antibody (G-4) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against full length smooth muscle myosin heavy chain of rat origin
  • recommended for detection of SM1 and SM2 smooth muscle myosin heavy chain isoforms of mouse, rat, human, bovine and porcine origin by WB, IP, IF, FCM and ELISA
  • phycoerythrin conjugate for intracellular FCM, sc-6956 PE, 100 tests
  • See 10 citations for MYH11 Antibody (G-4)
 

See additional Myosin Antibodies including Myosin, MYH, MYH1, MYH8, MYL, MYL1, MYL10, Mylc2b, Myosin Ia, Myosin Ib, Myosin Ic, Myosin Id, Myosin Ie, Myosin If, Myosin Ig, Myosin Ih, myosin IIa, Myosin IIIb, Myosin IXa, Myosin IXb, Myosin IXI, Myosin Va, Myosin Vb, Myosin Vc, Myosin VI, Myosin VIIa, Myosin VIIB, Myosin X, Myosin XIX, Myosin XVA, Myosin XVI, Myosin XVIIIa, Myosin XVIIIb, Myosin-neonatal, MRLC2, MYH2, MYL2, MRCL3, MYH3, MYL3, MYH4, MYL4, MYL5, MYH6, MYL6, MYL6B, MYH7, MYL7, MYH9, MYL9, MYH10, MYH11, MYH13, MYH14 and MYH15.

Also see Myosin Inhibitors for functional analysis of cellular responses to Myosin.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   FCM   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
MYH11 Antibody (G-4) sc-6956 200 µg/ml $279
MYH11 Antibody (G-4) PE sc-6956 PE 100 tests in 2 ml $303
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MYH11 siRNA (h) sc-76523 10 µM $258
MYH11 siRNA (m) sc-76524 10 µM $258
MYH11 (h)-PR sc-76523-PR 10 µM, 20 µl $23
MYH11 (m)-PR sc-76524-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MYH11 shRNA Plasmid (h) sc-76523-SH 20 µg $520
MYH11 shRNA Plasmid (m) sc-76524-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MYH11 shRNA (h) Lentiviral Particles sc-76523-V 200 µl $625
MYH11 shRNA (m) Lentiviral Particles sc-76524-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
A-10 Cell Lysate sc-3806 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MYH11 4629 16p13.11 NM_001040113, NM_001040114, NM_002474, NM_022844 P35749
 160745
Mouse Myh11 17880 16 A1 O08638
 N/A
 

Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins (such as MYH11), striated muscle Myosins and non-muscle Myosins. Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.

MYH11 Antibody (G-4) Product Citations
See how others have used MYH11 Antibody (G-4) and or MYH11 Antibody (G-4) conjugates.


10 total citations
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MYH11 Antibody (G-4) Data
Click on image to enlarge
sc-6956
MYH11 (G-4) PE: sc-6956 PE. Intracellular FCM analysis of fixed and permeabilized NIH/3T3 cells. Black line histogram represents the isotype control, normal mouse IgG1: sc-2866.
sc-6956
MYH11 (G-4): sc-6956. Western blot analysis of MYH11 expression in A-10 whole cell lysate.
sc-6956
MYH11 (G-4): sc-6956. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoskeletal rhodamine immunostaining of myosin heavy chain. Note also nuclear rhodamine immunostaining with Cdk4 (C-22): sc-260.
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