epitope mapping at the C-terminus of P-Selectin of mouse origin
recommended for detection of P-Selectin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine and bovine
P-Selectin Background Information Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.
P-Selectin (M-20) Product Citations
See how others have used P-Selectin (M-20): sc-6943 antibody and or P-Selectin (M-20) antibody conjugates.
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P-Selectin (M-20)
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P-Selectin (M-20): sc-6943. Western blot analysis of P-Selectin expression in human platelet extract.
P-Selectin (M-20): sc-6943. Immunoperoxidase staining of formalin-fixed human platelets and white blood cells showing membrane staining of platelets (A). Rhodamine immunofluorescence staining of methanol-fixed HUV-EC-C cells showing membrane localization (B).
P-Selectin (M-20): sc-6943. Western blot analysis ofP-Selectin expression in human platelet extract.
P-Selectin (M-20): sc-6943. Western blot analysis of P-Selectin expression in non-transfected: sc-117752 (A) and human P-Selectin transfected: sc-114655 (B) 293T whole cell lysates.
