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home » Signaling Intermediates » 4E-BP1 Antibody / 4E-BP1 Antibodies » 4E-BP1 (R-113): sc-6936

4E-BP1 (R-113) Antibody: sc-6936

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-117 representing full length rat 4E-BP1
  • recommended for detection of translational repressor 4E-BP1 of mouse, rat and human origin by WB, IP, IF and ELISA; may cross-react with 4E-BP2 and 4E-BP3; also reactive with additional species, including equine, canine, bovine and porcine
 
Additional 4E-BP1 Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human EIF4EBP1 1978 8p12 NM_004095 Q13541
 602223
Mouse Eif4ebp1 13685 8 A2 Q60876
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
4E-BP1 (R-113) sc-6936 200 µg/ml $279
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
HL-60 Whole Cell Lysate sc-2209 500 µg/200 µl $104
4E-BP1 (m): 293T Lysate sc-118030 100µg/200µl $205
4E-BP1 (h): 293T Lysate sc-116590 100µg/200µl $205
HeLa nuclear extract sc-2120 1000 µg $143

4E-BP1 Background Information
The translation of proteins from eukaryotic mRNA is initiated by the multisubunit complex eIF-4F, which associates with the mRNA 5' cap structure. eIF-4E, a component of eIF-4F, is responsible for binding to the 5' cap structure and for the assembly of the eIF-4F complex. The regulatory protein 4E-BP1, also referred to as PHAS-I, inhibits eIF-4E function. Phosphorylation of 4E-BP1 by S6 kinase p70, MAP kinases or PKCs causes the disassociation of 4E-BP1 from eIF-4E, promoting translation. A protein that is functionally related to 4E-BP1, designated 4E-BP2, also associates with eIF-4E.

4E-BP1 (R-113) Product Citations
See how others have used 4E-BP1 (R-113): sc-6936 antibody and or 4E-BP1 (R-113) antibody conjugates.


19 total citations
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4E-BP1 (R-113)
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sc-6936
Western blot analysis of His-tagged rat recombinant 4E-BP1 (A-C). Antibodies tested include 4E-BP1 (N-19): sc-6025 (A), 4E-BP1 (C-19): sc-6024 (B) and 4E-BP1 (R-113): sc-6936 (C).
sc-6936
4E-BP1 (R-113): sc-6936. Western blot analysis of 4E-BP1 expression in 3T3-L1 whole cell lysate.
sc-6936
4E-BP1 (R-113): sc-6936. Western blot analysis of 4E-BP1 expression in A-431 (A), K-562 (B) and HL-60 (C) whole cell lysates.
sc-6936
4E-BP1 (R-113): sc-6936. Western blot analysis of 4E-BP1 expression in non-transfected: sc-117752 (A) and mouse 4E-BP1 transfected: sc-118030 (B) 293T whole cell lysates.
sc-6936
4E-BP1 (R-113): sc-6936. Western blot analysis of 4E-BP1 expression in non-transfected: sc-117752 (A) and human 4E-BP1 transfected: sc-116590 (B) 293T whole cell lysates.
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