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home » Transcription Regulators » Clock Antibody / Clock Antibodies » Clock (S-19): sc-6927

Clock (S-19) Antibody: sc-6927

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of Clock of mouse origin
  • recommended for detection of Clock of mouse, rat, human, zebrafish and Xenopus origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine and porcine
  • blocking peptide, sc-6927 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6927 X, 200 µg/0.1 ml
 
Additional Clock Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CLOCK 9575 4q12 NM_004898 O15516
 601851
Mouse Clock 12753 5 C3.3 O08785
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Clock (S-19) sc-6927 200 µg/ml $279
Clock (S-19) P sc-6927 P
(peptide)
 100 µg/0.5 ml $61
Clock (S-19) X sc-6927 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Clock siRNA (h) sc-35074 10 µM $258
Clock siRNA (m) sc-35075 10 µM $258
Clock (h)-PR sc-35074-PR 10 µM $23
Clock (m)-PR sc-35075-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Clock shRNA Plasmid (h) sc-35074-SH 20 µg $520
Clock shRNA Plasmid (m) sc-35075-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Clock shRNA (h) Lentiviral Particles sc-35074-V 200 µl $625
Clock shRNA (m) Lentiviral Particles sc-35075-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
rat brain extract sc-2392 500 µg/200 µl $104

Clock Background Information
Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. Clock, a member of the basic-helix-loop-helix-PAS (bHLH-PAS) family of transcription factors, has also been identified as having circadian. Mutations within the Clock gene have been shown to increase the length of the endogenous period and to cause a loss of rhythmicity of circadian oscillations. Clock contains a DNA-binding domain, a protein dimerization domain and a glutamine-rich C-terminal region, which indicates transactivation capabilities. It has been speculated that Clock may regulate circadian rhythmicity in combination with other proteins such as Per. Per is also a PAS-domain containing protein that exhibits circadian function. Highest expression of Clock is seen in the hypothalamus and the eye.

Clock (S-19) Product Citations
See how others have used Clock (S-19): sc-6927 antibody and or Clock (S-19) antibody conjugates.


9 total citations
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Clock (S-19)
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sc-6927
Clock (S-19): sc-6927. Western blot analysis of Clock expression in rat hypothalamus (A) and rat brain (B) tissue extracts.
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