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USP14 Antibody (C-16): sc-69074

 |  Datasheet

(Based on data analysis)

  • USP14 Antibody (C-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of USP14 of human origin
  • recommended for detection of USP14 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-69074 P
 

See additional USP Antibodies including USP, USP1, USP17, USP27, USP46, USP2, USP3, USP4, USP5, USP6, USP9, USP9X, USP9Y, USP10, USP11, USP12, USP13, USP14, USP15, USP18, USP19, USP20, USP21, USP22, USP24, USP25, USP26, USP28, USP29, USP30, USP31, USP32, USP33, USP34, USP35, USP36, USP37, USP38, USP39, USP40, USP42, USP43, USP44, USP45, USP47, USP48, USP49, USP50, USP51, USP52, USP53, USP54 and USP17L4.

Also see USP14 Inhibitors for functional analysis of cellular responses to USP14.


Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
USP14 Antibody (C-16) sc-69074 200 µg/ml $279
USP14 (C-16) P sc-69074 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
USP14 siRNA (h) sc-76817 10 µM $258
USP14 siRNA (m) sc-76818 10 µM $258
USP14 (h)-PR sc-76817-PR 10 µM, 20 µl $23
USP14 (m)-PR sc-76818-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
USP14 shRNA Plasmid (h) sc-76817-SH 20 µg $520
USP14 shRNA Plasmid (m) sc-76818-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
USP14 shRNA (h) Lentiviral Particles sc-76817-V 200 µl $625
USP14 shRNA (m) Lentiviral Particles sc-76818-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human USP14 9097 18p11.32 P54578
607274
Mouse Usp14 59025 18 A1 Q9JMA1
N/A
 


The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP14 (ubiquitin specific peptidase 14), also known as TGT (tRNA-guanine transglycosylase), is a cytoplasmic protein that belongs to the ubiquitin-specific processing family of deubiquitinating enzymes. Existing as a homodimer within the cell, USP14 functions to cleave ubiquitin residues from both ubiquitinylated proteins and ubiquitin-fused precursors, thereby saving these proteins from proteasomal degradation. In mice, defects or mutations in the gene encoding USP14 cause retarded growth or fetal death, indicating that USP14 plays a key role in early developmental processes. Multiple isoforms of USP14 are expressed due to alternative splicing events.