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MCR Antibody (C-19): sc-6861

 |  Datasheet

(Based on data analysis)

  • MCR Antibody (C-19) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of MCR of human origin
  • recommended for detection of MCR of mouse, rat and human origin by WB, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-6861 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6861 X, 200 µg/0.1 ml
  • See 6 citations for MCR Antibody (C-19)
 

See additional MCR Antibodies.

Also see MCR Inhibitors or MCR Activators for functional analysis of cellular responses to MCR.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   IHC(P)   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
MCR Antibody (C-19) sc-6861 200 µg/ml $279
MCR (C-19) P sc-6861 P
(peptide)
 100 µg/0.5 ml $61
MCR Antibody (C-19) X sc-6861 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MCR siRNA (h) sc-38836 10 µM $258
MCR siRNA (m) sc-38837 10 µM $258
MCR (h)-PR sc-38836-PR 10 µM, 20 µl $23
MCR (m)-PR sc-38837-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MCR shRNA Plasmid (h) sc-38836-SH 20 µg $520
MCR shRNA Plasmid (m) sc-38837-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
MCR shRNA (h) Lentiviral Particles sc-38836-V 200 µl $625
MCR shRNA (m) Lentiviral Particles sc-38837-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NR3C2 4306 4q31.23 NM_000901 P08235
 605115
Mouse Nr3c2 110784 8 C1 Q8VII8
 N/A
 

Mineralocorticoid hormones are primarily found in epithelial tissues where they function as regulators of Na+, K+ and H+ ion transport. Aldosterone is a mineralocorticoid that has been shown to regulate electrolyte excretion and intravascular volume and is therefore involved in blood pressure regulation. Mineralocorticoid receptor (MCR or MR) is a member of the steroid/thyroid/retinoic nuclear hormone receptor superfamily that has been shown to activate gene transcription in response to aldosterone binding. Regulation of the mineralocorticoid receptors occurs through either receptor down-regulation (negative autoregulation) or hormone-mediated upregulation (positive autoregulation). MCR association with HSP 90 appears to be required for hormone binding to MCR and subsequent MCR activation.

MCR Antibody (C-19) Product Citations
See how others have used MCR Antibody (C-19) and or MCR Antibody (C-19) conjugates.


6 total citations
Loading citations.
 
MCR Antibody (C-19) Data
Click on image to enlarge
sc-6861
MCR (C-19): sc-6861. Immunoperoxidase staining of formalin-fixed, paraffin-embedded mouse testis tissue showing nuclear envelope localization.
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