MMP-3 (C-19) Antibody sc-6839

santa cruz biotechnology, inc.

Research Products
Primary Antibodies Secondary Antibodies, Control Antibodies and Normal Sera Phospho-Specific Antibodies Flow Cytometry Antibodies for IHC (Paraffin) Staining Protein A, G PLUS and L-Agarose siRNA and shRNA (plasmid and lentivirus) Products Tissue Extracts, Cell Lysates and Proteins Transfected Cell Lysates Specialty Reagents and Buffers Veterinary Research Antibodies
Chemicals
Biochemicals Prepared Buffers Buffers and Standard Lab Chemicals Stains and Dyes Solvents HRP and AP Substrates
Lab Supplies
Lab Supplies UltraCruz™ExactaCruz™CrystalCruz™
Animal Health
Animal Health Promotionals
What's New
Promotionals Animal Health Promotionals LIF Protein Veterinary Research Antibodies Monoclonal Antibodies Polyclonal Antibodies
Company Info
Company Info Contact Us Protocols Product Citations Datasheets / MSDS Technical Service Catalog Request Chromosome DBase Cruz Credits™Investigator Awards Job Opportunities Distributors

MMP-3 (C-19) Antibody: sc-6839	\| Datasheet

goat polyclonal IgG, 200 µg/ml; also available as rabbit IgG, 200 µg/ml, sc-6839-R
epitope mapping at the C-terminus of MMP-3 of human origin
recommended for detection of MMP-3 and, to a lesser extent, a broad range of MMP family members of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
blocking peptide, sc-6839 P

Additional MMP Antibodies ...

Ordering InformationProduct Citations

Recommended Support Products:

(click button of application of choice)

WB IP IF IHC(P) siRNA

Species	Gene Name	Gene ID	Chromosome Location	Isoform (mRNA) Accession #	Protein Accession #	OMIM™ Number

Human	MMP3	4314	11q22.2	NM_002422	P08254	185250
Mouse	Mmp3	17392	9 A1		P28862	N/A

Set Currency

Ordering Information

Product Name	Catalog #	Unit	Price
MMP-3 (C-19)	sc-6839	200 µg/ml	$279
MMP-3 (C-19) P	sc-6839 P (peptide)	100 µg/0.5 ml	$61
MMP-3 (C-19)-R	sc-6839-R	200 µg/ml	$279

MMP-3 Background Information
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, -2 and -3 respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

MMP-3 (C-19) Product Citations

See how others have used MMP-3 (C-19): sc-6839 antibody and or MMP-3 (C-19) antibody conjugates.