raised against amino acids 47-218 mapping near the N-terminus of VEPH1 of human origin
recommended for detection of VEPH1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, bovine and porcine
VEPH1 Background Information Ventricular zone-expressed PH domain-containing protein homolog 1 (VEPH1), also known as KIAA1692 or Protein melted, is a 833 amino acid protein belonging to the MELT/VEPH family. VEPH1 is a peripheral membrane protein localized to the cytoplasmic side. VEPH1 has one PH domain which is required for the membrane targeting of the protein. The human gene encoding VEPH1 is 76% homologous to the Drosophila VEPH1 gene which encodes a protein that acts as a regulator of the insulin signaling pathway. It is thought that this role of VEPH1 is conserved across species. VEPH1 exists as three isoforms produced by alternative splicing.
