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CSMD1 Antibody (K-14): sc-68278

 |  Datasheet

(Based on data analysis)
  • CSMD1 Antibody (K-14) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an extracellular domain of CSMD1 of human origin
  • recommended for detection of CSMD1 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-68278 P
 

See additional CSMD Antibodies including CSMD, CSMD1, CSMD2 and CSMD3.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CSMD1 Antibody (K-14) sc-68278 200 µg/ml $279
CSMD1 (K-14) P sc-68278 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CSMD1 siRNA (h) sc-77034 10 µM $258
CSMD1 siRNA (m) sc-77035 10 µM $258
CSMD1 (h)-PR sc-77034-PR 10 µM, 20 µl $23
CSMD1 (m)-PR sc-77035-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CSMD1 shRNA Plasmid (h) sc-77034-SH 20 µg $520
CSMD1 shRNA Plasmid (m) sc-77035-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CSMD1 shRNA (h) Lentiviral Particles sc-77034-V 200 µl $625
CSMD1 shRNA (m) Lentiviral Particles sc-77035-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CSMD1 64478 8p23.2 Q96PZ7
 608397
Mouse Csmd1 94109 8 A1.1 Q923L3
 N/A
 

The CUB and sushi domain-containing proteins, CSMD1-3, are membrane proteins that are involved in cell-cell adhesion and are weakly expressed in most tissues, with higher levels of expression observed in the cerebellum and hippocampus. CSMD1 is part of the complement system that defends against pathogens through either the classical pathway or the alternative pathway. Located primarily in nerve growth cones, CSMD1 blocks the classical pathway of the immune system and is thought to be involved in tumor suppression, as defects in the gene encoding CSMD1 are associated with squamous cell carcinomas. CSMD2 and CSMD3 are located primarily in the brain and are implicated in some forms of head and neck cancer. Additionally, the CSMD3 gene is a candidate for induction of epileptic seizures.