Date published: 2025-10-26

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Aggrecan Antibodies

Santa Cruz Biotechnology features a diverse variety of Aggrecan Antibodies for investigating aggrecan's role in various biological processes. Aggrecan Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Aggrecan is a key component of cartilage and plays a crucial role in maintaining the structural integrity and resilience of cartilage tissue. As a major proteoglycan in cartilage, aggrecan enables joints to withstand compression and maintain flexibility. The protein's unique structure allows it to form large aggregates that give cartilage its characteristic mechanical properties. Research focusing on aggrecan has revealed its significance in cartilage development, maintenance, and repair. Understanding aggrecan's molecular mechanisms and interactions provides valuable insights into conditions like osteoarthritis and other cartilage-related diseases. Investigating aggrecan's role in tissue engineering and regenerative medicine opens new possibilities for therapeutic interventions. Santa Cruz Biotechnology monoclonal antibodies for aggrecan research support scientists worldwide in advancing our understanding of cartilage biology and developing new treatments for joint diseases.

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Aggrecan Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

aggrecan Antibody (4F4)

sc-33695mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
38
(13)

aggrecan Antibody (3H524)

sc-70333mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
4
(1)

aggrecan Antibody (5J14)

sc-70334mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
3
(1)

aggrecan Antibody (3H525)

sc-70332mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
3
(1)

aggrecan/brevican Antibody (D-4)

sc-166951mouse IgM κ2261-2280 (h)WB, IP, IF, ELISAm, r, h
15
(5)

Aggrecan CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

aggrecan CRISPR/Cas9 KO Plasmid (h)

sc-400760hGene KnockoutGFP0
(0)

aggrecan CRISPR/Cas9 KO Plasmid (h2)

sc-400760-KO-2hGene KnockoutGFP0
(0)

aggrecan HDR Plasmid (h2)

sc-400760-HDR-2hHomology Directed RepairPuromycin0
(0)

aggrecan Double Nickase Plasmid (h)

sc-400760-NIChGene KnockoutPuromycin0
(0)

aggrecan Double Nickase Plasmid (h2)

sc-400760-NIC-2hGene KnockoutPuromycin0
(0)

aggrecan CRISPR/Cas9 KO Plasmid (m)

sc-419039mGene KnockoutGFP0
(0)

aggrecan Double Nickase Plasmid (m)

sc-419039-NICmGene KnockoutPuromycin0
(0)

aggrecan Double Nickase Plasmid (m2)

sc-419039-NIC-2mGene KnockoutPuromycin0
(0)

Aggrecan CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

aggrecan CRISPR Activation Plasmid (h)

sc-400760-ACThGene ActivationPuro, Blast, Hygro0
(0)

aggrecan CRISPR Activation Plasmid (h2)

sc-400760-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

aggrecan Lentiviral Activation Particles (h)

sc-400760-LAChGene ActivationPuro, Blast, Hygro0
(0)

aggrecan Lentiviral Activation Particles (h2)

sc-400760-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

aggrecan CRISPR Activation Plasmid (m)

sc-419039-ACTmGene ActivationPuro, Blast, Hygro0
(0)

aggrecan CRISPR Activation Plasmid (m2)

sc-419039-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

aggrecan Lentiviral Activation Particles (m)

sc-419039-LACmGene ActivationPuro, Blast, Hygro0
(0)

aggrecan Lentiviral Activation Particles (m2)

sc-419039-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Aggrecan siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

aggrecan siRNA (h)

sc-41897hGene SilencingN/A0
(0)

aggrecan shRNA Plasmid (h)

sc-41897-SHhGene SilencingPuromycin0
(0)

aggrecan shRNA (h) Lentiviral Particles

sc-41897-VhGene SilencingPuromycin0
(0)

aggrecan siRNA (m)

sc-41898mGene SilencingN/A0
(0)

aggrecan shRNA Plasmid (m)

sc-41898-SHmGene SilencingPuromycin0
(0)

aggrecan shRNA (m) Lentiviral Particles

sc-41898-VmGene SilencingPuromycin0
(0)

aggrecan 1 siRNA (bovine)

sc-270555bovineGene SilencingN/A0
(0)

aggrecan 1 shRNA Plasmid (bovine)

sc-270555-SHbovineGene SilencingPuromycin0
(0)

aggrecan 1 shRNA (bovine) Lentiviral Particles

sc-270555-VbovineGene SilencingPuromycin0
(0)