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MacroH2A (H-39) Antibody: sc-67322

 |  Datasheet
  • rabbit polyclonal IgG, 200µg/ml
  • epitope corresponding to amino acids 144-182 mapping within an internal region of MacroH2A of human origin
  • recommended for detection of MacroH2A of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and bovine
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-67322 X, 200 µg/0.1 ml
 
Additional MacroH2 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human H2AFY2 55506 10q22.1 NM_018649 Q9P0M6
n/a
Mouse H2afy2 404634 10 B4 Q8CCK0
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A (H-39) sc-67322 200 µg/ml $279
MacroH2A (H-39) X sc-67322 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A siRNA (h) sc-62575 10 µM $258
MacroH2A siRNA (m) sc-62576 10 µM $258
MacroH2A (h)-PR sc-62575-PR 10 µM $23
MacroH2A (m)-PR sc-62576-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A shRNA Plasmid (h) sc-62575-SH 20 µg $520
MacroH2A shRNA Plasmid (m) sc-62576-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A shRNA (h) Lentiviral Particles sc-62575-V 200 µl $625
MacroH2A shRNA (m) Lentiviral Particles sc-62576-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MacroH2A (h): 293 Lysate sc-111902 100µg/200µl $205

MacroH2A Background Information
Eukaryotic histones are water soluble, basic nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer. The octamer consists of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. MacroH2A, also called core histone MacroH2A2 (mH2A2), is a variant Histone H2A, originally isolated in rat liver, that is nearly three times as large as conventional H2A. MacroH2A may be involved in stable X chromosome inactivation as it is enriched in inactive X chromosome chromatin.

MacroH2A (H-39)
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MacroH2A (H-39): sc-67322. Western blot analysis of human recombinant MacroH2A fusion protein.
MacroH2A (H-39): sc-67322. Western blot analysis of MacroH2A expression in human MacroH2A transfected: sc-111902 (A) and non-transfected: sc-110760 (B) 293 whole cell lysates.
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