epitope corresponding to amino acids 1-280 representing full length BAM32 of human origin
recommended for detection of BAM32 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine and bovine
BAM32 Background Information B cell adapter molecule (BAM32) is also designated dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC g2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.
BAM32 (FL-280)
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BAM32 (FL-280): sc-67166. Western blot analysis of BAM32 expression in non-transfected: sc-117752 (A) and human BAM32 transfected: sc-113815 (B) 293T whole cell lysates.
BAM32 (FL-280): sc-67166. Western blot analysis of BAM32 expression in non-transfected: sc-117752 (A) and human BAM32 transfected: sc-174819 (B) 293T whole cell lysates.
BAM32 (FL-280): sc-67166. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing membrane staining of exocrine glandular cells and islets of Langerhans at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
