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VDUP1 Antibody (H-115): sc-67134

 |  Datasheet

(Based on data analysis)

  • VDUP1 Antibody (H-115) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1-115 mapping at the N-terminus of VDUP1 of human origin
  • recommended for detection of VDUP1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • See 1 citations for VDUP1 Antibody (H-115)
 
Full-length VDUP1 protein sequence with immunogen highlighted:
MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ

See additional VDUP1 Antibodies.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
VDUP1 Antibody (H-115) sc-67134 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
VDUP1 siRNA (h) sc-44943 10 µM $258
VDUP1 siRNA (m) sc-44944 10 µM $258
VDUP1 siRNA (h)-PR sc-44943-PR 10 µM, 20 µl $23
VDUP1 siRNA (m)-PR sc-44944-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
VDUP1 shRNA Plasmid (h) sc-44943-SH 20 µg $520
VDUP1 shRNA Plasmid (m) sc-44944-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
VDUP1 siRNA shRNA (h) Lentiviral Particles sc-44943-V 200 µl $625
VDUP1 siRNA shRNA (m) Lentiviral Particles sc-44944-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HL-60 Whole Cell Lysate sc-2209 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human TXNIP 10628 1q21.1 NM_006472 Q9H3M7
 606599
Mouse Txnip 56338 3 F2.1 Q8BG60
 N/A
 

The gene encoding vitamin D3 upregulated protein 1 (VDUP1) is upregulated by 1,25(OH)2D3 in response to various stresses, including ROS, UV and heat shock. The transcription factor HSF may be involved in this regulation. VDUP1 also functions as a natural antagonist of TRX, and displays tumor-suppressive activity by inducing cell cycle arrest at the G0/G1 phase. The presence of VDUP1 is required for CD122 expression and natural killer (NK) cell maturation, but its effect is minimal during the development of T and B cells. The gene encoding human VDUP1 maps to chromosome 1q21, and its protein product shows ubiquitous expression in various tissues and localizes to the cytoplasm. VDUP1 may also be a useful therapeutic target for melanoma.

VDUP1 Antibody (H-115) Product Citations
See how others have used VDUP1 Antibody (H-115) and or VDUP1 Antibody (H-115) conjugates.


1 total citations
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VDUP1 Antibody (H-115) Data
Click on image to enlarge
sc-67134
VDUP1 (H-115): sc-67134. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and membrane localization.
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