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- rabbit polyclonal IgG, 200µg/ml
- epitope corresponding to amino acids 1-300 mapping at the N-terminus of PBEF of human origin
- recommended for detection of Pre-B cell enhancing factor of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine and porcine
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
PBEF1 |
10135 |
7q22.2 |
NM_005746 |
P43490
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608764 |
| Mouse |
Nampt |
59027 |
12 A3 |
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Q99KQ4
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N/A |
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PBEF Background Information
Pre-B cell-enhancing factor (PBEF), also designated nicotinamide phosphoribosyltransferase (Nampt) or visfatin, belongs to the NAPRTase family of proteins. PBEF may be involved in enhancing the effect of IL-7 and SCF on the formation of early B-lineage precursor colonies. It is involved in the catalysis of nicotinamide with 5-phosphoribosyl-1-pyrophosphate, yielding nicotinamide mononucleotide, which is important in NAD biosynthesis. This is a rate limiting step in the NAD biosynthesis pathway. Highly enriched in the visceral fat of both human and mouse, PBEF expression levels in plasma increase during the development of obesity. PBEF is a cytoplasmic protein expressed primarily in bone marrow, muscle and liver tissue, but it can also be detected in placenta, lung, kidney and heart tissue.
| PBEF (H-300) Product Citations |
See how others have used PBEF (H-300): sc-67020 antibody and or PBEF (H-300) antibody conjugates.
2 total citations Loading citations.
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PBEF (H-300)
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PBEF (H-300): sc-67020. Western blot analysis of PBEF expression in HL-60 whole cell lysate.
PBEF (H-300): sc-67020. Western blot analysis of PBEF expression in non-transfected 293T: sc-117752 (A), human PBEF transfected 293T: sc-111747 (B) and HL-60 (C) whole cell lysates. PBEF (H-300): sc-67020. Western blot analysis of PBEF expression in non-transfected: sc-117752 (A) and mouse PBEF transfected: sc-122402 (B) 293T whole cell lysates. PBEF (H-300): sc-67020. Western blot analysis of PBEF expression in non-transfected 293T: sc-117752 (A), human PBEF transfected 293T: sc-111747 (B) and HL-60 (C) whole cell lysates. |
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