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Polyoma virus VP1 Antibody (9F11): sc-65927


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  • Polyoma virus VP1 Antibody (9F11) is a mouse monoclonal IgG1 provided at 100 µg/ml
  • raised against a chimeric hamster polyomavirus VP1/human MUC1 sequence
  • recommended for detection of major capsid protein VP1 of hamster Polyoma virus origin by WB, IF and IHC(P)

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Product NameCatalog #UnitPriceQtyAddFavorites
Polyoma virus VP1 Antibody (9F11) sc-65927 100 µg/ml $279

Human Polyoma virus (JV) belongs to the genus Polyomavirus. JV is capable of transforming fetal brain cells and human amnion cells in vitro and can lead to tumor development in other species. JV VP1 (gp01) is one of the three constituent capsid proteins produced by the JV virion. JV also contains the capsid proteins VP2 (gp02) and VP3 (gp03) as well as a viral minichromosome. JV VP1 is the primary capsid protein, comprising 75% of the total capsid shell protein. It is thought that the tumor inducing properties of JV may be credited to an interaction between VP1, cellular retinoblastoma protein and p53. In immunocompromised individuals JV has been known to cause progressive multifocal leukoencephalopathy (PML). About 10% of the capsid proteins are made from VP2 and VP3.

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