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Clathrin HC (C-20) Antibody: sc-6579 |
| Datasheet |
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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of Clathrin HC of human origin
- recommended for detection of clathrin heavy chain of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-6579 P
- fluorescein (sc-6579 FITC) and rhodamine (sc-6579 TRITC) conjugates for immunofluorescence, 200 µg/ml
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
CLTC |
1213 |
17q23.1 |
NM_004859 |
Q00610
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118955 |
| Mouse |
Cltc |
67300 |
11 C |
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Q68FD5
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N/A |
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Clathrin HC Background Information
Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network (1,2). In receptor-mediated endocytosis, receptor proteins are englufed by clathrin-coated vesicles (3,4). Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure (5,6). Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site (7). The proximal segment of the clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure (7).
| Clathrin HC (C-20) Product Citations |
See how others have used Clathrin HC (C-20): sc-6579 antibody and or Clathrin HC (C-20) antibody conjugates.
8 total citations Loading citations.
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Clathrin HC (C-20)
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Clathrin HC (C-20): sc-6579. Western blot analysis of Clathrin heavy chain expression in HeLa (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.
Clathrin HC (C-20): sc-6579. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue (A) and rhodamine immunofluorescence staining of methanol-fixed A-431 cells (B) showing localized staining within the cytoplasm.
Clathrin HC (C-20): sc-6579. Western blot analysis of Clathrin HC expression in non-transfected 293T: sc-117752 (A), human Clathrin HC transfected 293T: sc-116149 (B) and HeLa (C) whole cell lysates. Clathrin HC (C-20): sc-6579. Western blot analysis of Clathrin HC expression in MCF7 whole cell lysate.
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