TAF I p95 Background Information For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter (1-3). Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs) (4,5). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB (6-8). The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter- and RNA polymerase-specific complexes (6).
TAF I p95 (M-18) Product Citations
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TAF I p95 (M-18)
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TAF I p95 (M-18): sc-6567. Western blot analysis of TAF I p95 expression in 3611-RF nuclear extract.
TAF I p95 (M-18): sc-6567. Western blot analysis of TAF I p95 expression in 3611-RF nuclear extract.
TAF I p95 (M-18): sc-6567. Western blot analysis of TAF I p110 expression in non-transfected: sc-117752 (A) and truncated human TAF I p110 transfected: sc-114680 (B) 293T whole cell lysates.