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HNF-4α Antibody (S-20): sc-6557

 |  Datasheet

(Based on data analysis)

  • HNF-4α Antibody (S-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of HNF-4α of human origin
  • recommended for detection of HNF-4α of human, and, to a lesser extent, mouse and rat origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-6557 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6557 X, 200 µg/0.1 ml
  • See 7 citations for HNF-4α Antibody (S-20)
 

See additional HNF Antibodies including HNF, HNF-1, HNF-1 alpha, HNF-1 beta, HNF-3 alpha, HNF-3 beta, HNF-3 gamma, HNF-4 alpha, HNF-4 gamma and HNF-6.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
HNF-4α Antibody (S-20) sc-6557 200 µg/ml $279
HNF-4α (S-20) P sc-6557 P
(peptide)
 100 µg/0.5 ml $61
HNF-4α Antibody (S-20) X sc-6557 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HNF-4α siRNA (h) sc-35573 10 µM $258
HNF-4α siRNA (m) sc-35574 10 µM $258
HNF-4α (h)-PR sc-35573-PR 10 µM, 20 µl $23
HNF-4α (m)-PR sc-35574-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HNF-4α shRNA Plasmid (h) sc-35573-SH 20 µg $520
HNF-4α shRNA Plasmid (m) sc-35574-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HNF-4α shRNA (h) Lentiviral Particles sc-35573-V 200 µl $625
HNF-4α shRNA (m) Lentiviral Particles sc-35574-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HNF-4α (m): 293T Lysate sc-126960 100 µg/200 µl $205
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HNF4A 3172 20q13.12 NM_000457, NM_001030003, NM_001030004, NM_175914, NM_178849, NM_178850 P41235
 600281
 

HNF-1 (å and ∫), HNF-3 (å, ∫ and ©), HNF-4 (å and ©) and HNF-6 compose, in part, a homoeprotein family designated the Hepatocyte Nuclear Factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF-3å, HNF-3∫ and HNF-3© regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3å and HNF-3∫ have also been shown to be involved in gastrulation events such as body axis formation. HNF-4å and HNF-4© have been shown to be important for early embryo development. HNF-4å is expressed in liver, kidney, pancreas, small intestine, testis and colon; and HNF-4© is expressed in each of these tissues except liver. HNF-6 has been shown to bind to the promoter of HNF-3∫, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation. Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, including cytochrome P450 2C13 and å-1 antitrypsin.

HNF-4α Antibody (S-20) Product Citations
See how others have used HNF-4α Antibody (S-20) and or HNF-4α Antibody (S-20) conjugates.


7 total citations
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HNF-4α Antibody (S-20) Data
Click on image to enlarge
sc-6557
HNF-4α (S-20): sc-6557. Immunofluorescence staining of methanol-fixed Hep G2 cells showing nuclear localization.
sc-6557
HNF-4α (S-20): sc-6557. Western blot analysis of HNF-4α expression in non-transfected 293T: sc-117752 (A), mouse HNF-4α transfected 293T: sc-126960 (B) and Hep G2 (C) whole cell lysates.
sc-6557
HNF-4α (S-20): sc-6557. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing nuclear staining of glandular cells.
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