santa cruz biotechnology, inc.
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- mouse monoclonal IgG1, 100µg/ml
- raised against IFN-ω of human origin
- recommended for detection of IFN-ω of human origin by ELISA
- also provided azide-free for blocking of IFN-ω, sc-65420 L, 100 µg/0.1 ml
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
IFNW1 |
3467 |
9p21.3 |
NM_002177 |
P05000
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n/a |
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IFN-ω Background Information
The genes encoding type I interferons (IFNs), which include 14 IFN-å genes, one IFN-∫ gene, one IFN-w (also known as IFN-å II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-å and -∫ are cytokines that are widely known to induce potent anti-viral activity. IFN-å and -∫ exert a variety of other biological effects, including anti-tumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-å, IFN-∫ or IFN-©, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The Type I interferon receptor (IFN-åR) interacts with IFN-å, IFN-∫ and IFN-w, and seems to be a multisubunit receptor. |
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