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home » Synthesis and Degradation » LASS Antibody / LASS Antibodies » LASS4 (C-19): sc-65112

LASS4 (C-19) Antibody: sc-65112

  |  Datasheet
  • goat polyclonal IgG, 200µg/ml
  • epitope mapping at the C-terminus of LASS4 of human origin
  • recommended for detection of LASS4 of human origin by WB, IP, IF, IHC(P) and ELISA
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-65112 X, 200 µg/0.1 ml
  • blocking peptide, sc-65112 P
 
Additional LASS Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human LASS4 79603 19p13.2 NM_024552 Q9HA82
 n/a
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 (C-19) sc-65112 200 µg/ml $279
LASS4 (C-19) P sc-65112 P
(peptide)
 100 µg/0.5 ml $61
LASS4 (C-19) X sc-65112 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 siRNA (h) sc-62549 10 µM $258
LASS4 (h)-PR sc-62549-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 shRNA Plasmid (h) sc-62549-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
LASS4 shRNA (h) Lentiviral Particles sc-62549-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
LASS4 (m): 293T Lysate sc-121305 100µg/200µl $205
LASS4 (h2): 293T Lysate sc-173489 100µg/200µl $205
PC-3 Cell Lysate sc-2220 500 µg/200 µl $104

LASS4 Background Information
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
LASS4 (C-19)
Click on image to enlarge
sc-65112
LASS4 (C-19): sc-65112. Western blot analysis of LASS4 expression in LNCaP (A), PC-3 (B), SK-MEL-28 (C) and U-698-M (D) whole cell lysates.
sc-65112
LASS4 (C-19): sc-65112. Western blot analysis of LASS4 expression in non-transfected: sc-117752 (A) and human LASS4 transfected: sc-173489 (B) 293T whole cell lysates.
sc-65112
LASS4 (C-19): sc-65112. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing cytoplasmic staining of glandular cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
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