santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Cell Cycle Proteins » Cdc Antibody / Cdc Antibodies » Cdc27 (C-20): sc-6392

Cdc27 (C-20) Antibody: sc-6392

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of Cdc27 of human origin
  • recommended for detection of Cdc27 of human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-6392 P
 
Additional Cdc Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CDC27 996 17q21.32 NM_001256 P30260
 116946
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc27 (C-20) sc-6392 200 µg/ml $279
Cdc27 (C-20) P sc-6392 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc27 siRNA (h) sc-77362 10 µM $258
Cdc27 (h)-PR sc-77362-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc27 shRNA Plasmid (h) sc-77362-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdc27 shRNA (h) Lentiviral Particles sc-77362-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 nuclear extract sc-2130 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143
Jurkat + PMA nuclear extract sc-2133 1000 µg $143
A-431 nuclear extract sc-2122 1000 µg $143
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
K-562 + PMA nuclear extract sc-2131 1000 µg $143

Cdc27 Background Information
Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with Hsp90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.

Cdc27 (C-20) Product Citations
See how others have used Cdc27 (C-20): sc-6392 antibody and or Cdc27 (C-20) antibody conjugates.


2 total citations
Loading citations.
 
Cdc27 (C-20)
Click on image to enlarge
sc-6392
Cdc27 (C-20): sc-6392. Western blot analysis of Cdc27 expression in control K-562 (A), phorbol-induced K-562 (B), control Jurkat (C) and phorbol-induced Jurkat (D) nuclear extracts.
sc-6392
Cdc27 (C-20): sc-6392. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung tumor showing nuclear staining.
sc-6392
Cdc27 (C-20): sc-6392. Immunofluorescence staining of methanol-fixed K-562 cells showing nuclear localization.
Download
Datasheets
Get Adobe Acrobat Reader