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- rabbit polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of Elf-1 of human origin
- recommended for detection of Elf-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine and canine
- blocking peptide, sc-631 P
- HRP conjugate, sc-631 HRP, 200 µg/ml
- TransCruz reagent for Gel Supershift and ChIP applications, sc-631 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
ELF1 |
1997 |
13q14.11 |
NM_172373 |
P32519
|
189973 |
| Mouse |
Elf1 |
13709 |
14 D3 |
|
Q60775
|
N/A |
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Elf-1 Background Information
Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA-binding activity of all members of the Ets gene family. Elf-1 is a lymphoid-specific member of the Ets family that has been shown to regulate inducible gene expression during T cell activation. Elf-1 contains a sequence motif that is highly related to the Rb-binding sites common to several viral oncoproteins and binds to the pocket region of Rb both in vivo and in vitro.
| Elf-1 (C-20) Product Citations |
See how others have used Elf-1 (C-20): sc-631 antibody and or Elf-1 (C-20) antibody conjugates.
16 total citations Loading citations.
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Elf-1 (C-20)
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Elf-1 (C-20): sc-631. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma tissue showing intense nuclear staining.
Elf-1 (C-20): sc-631. Western blot analysis of Elf-1 expression in HeLa (A), A-431 (B), A-673 (C), K-562 (D) and Jurkat (E) nuclear extracts.
Elf-1 (C-20): sc-631. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
Elf-1 (C-20): sc-631. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing nuclear staining of glandular cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Elf-1 (C-20): sc-631. Western blot analysis of Elf-1 expression in 293T (A) and HeLa (B) whole cell lysates.
Elf-1 (C-20): sc-631. Western blot analysis of Elf-1 expression in non-transfected: sc-117752 (A) and human Elf-1 transfected: sc-176605 (B) 293T whole cell lysates. |
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