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home » Steroid Receptors » PPAR Antibody / PPAR Antibodies » PPARγ (K-18): sc-6284

PPARγ (K-18) Antibody: sc-6284

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the C-terminus of PPARγ of human origin
  • recommended for detection of PPARγ1 and PPARγ2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-6284 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6284 X, 200 µg/0.1 ml
 
Additional PPAR Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PPARG 5468 3p25.2 NM_005037, NM_015869, NM_138711, NM_138712 P37231
 609830
Mouse Pparg 19016 6 E3 P37238
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PPARγ (K-18) sc-6284 200 µg/ml $279
PPARγ (K-18) P sc-6284 P
(peptide)
 100 µg/0.5 ml $61
PPARγ (K-18) X sc-6284 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PPARγ siRNA (h) sc-29455 10 µM $258
PPARγ siRNA (m) sc-29456 10 µM $258
PPARγ siRNA (h2) sc-44220 10 µM $258
PPARγ (h)-PR sc-29455-PR 10 µM $23
PPARγ (m)-PR sc-29456-PR 10 µM $23
PPARγ (h2)-PR sc-44220-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PPARγ shRNA Plasmid (h) sc-29455-SH 20 µg $520
PPARγ shRNA Plasmid (m) sc-29456-SH 20 µg $520
PPARγ shRNA Plasmid (h2) sc-44220-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PPARγ shRNA (h) Lentiviral Particles sc-29455-V 200 µl $625
PPARγ shRNA (m) Lentiviral Particles sc-29456-V 200 µl $625
PPARγ shRNA (h2) Lentiviral Particles sc-44220-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
U-937 Cell Lysate sc-2239 500 µg/200 µl $104
THP-1 Cell Lysate sc-2238 500 µg/200 µl $104
3T3-L1 Cell Lysate sc-2243 500 µg/200 µl $104

PPARγ Background Information
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor subfamily of transcription factors. PPARs form heterodimers with retinoid X receptors (RXRs). These heterodimers regulate transcription of genes involved in insulin action, adipocyte differentiation, lipid metabolism and inflammation. PPAR© is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR© activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPAR© may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPAR©2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPAR©2 gene maybe correlated with abdominal obesity in type 2 diabetes.

PPARγ (K-18) Product Citations
See how others have used PPARγ (K-18): sc-6284 antibody and or PPARγ (K-18) antibody conjugates.


6 total citations
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PPARγ (K-18)
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sc-6284
PPARγ (K-18): sc-6284. Western blot analysis of PPARγ expression in non-transfected: sc-117752 (A) and mouse PPARγ transfected: sc-122729 (B) 293T whole cell lysates.
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