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home » Cell Cycle Proteins » Cdk Antibody / Cdk Antibodies » Cdk2 (D-12): sc-6248

Cdk2 (D-12) Antibody: sc-6248

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against amino acids 1-298 representing full length Cdk2 of human origin
  • recommended for detection of Cdk2 of mouse, rat and human origin by WB, IP, IF and ELISA
  • fluorescein (sc-6248 FITC) and rhodamine (sc-6248 TRITC) conjugates for immunofluorescence, 200 µg/ml
  • Alexa Fluor® 405 (sc-6248 AF405), Alexa Fluor® 488 (sc-6248 AF488) and Alexa Fluor® 647 (sc-6248 AF647) conjugates for immunofluorescence; 100 µg/2 ml
 
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Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CDK2 1017 12q13.2 NM_001798, NM_052827 P24941
 116953
Mouse Cdk2 12566 10 D3 P97377
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 (D-12) sc-6248 200 µg/ml $279
Cdk2 (D-12) Alexa Fluor® 405 sc-6248 AF405 100 µg/2 ml $314
Cdk2 (D-12) Alexa Fluor® 488 sc-6248 AF488 100 µg/2 ml $314
Cdk2 (D-12) Alexa Fluor® 647 sc-6248 AF647 100 µg/2 ml $314
Cdk2 (D-12) FITC sc-6248 FITC 200 µg/ml $282
Cdk2 (D-12) TRITC sc-6248 TRITC 200 µg/ml $282
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 siRNA (h) sc-29259 10 µM $258
Cdk2 siRNA (m) sc-29260 10 µM $258
Cdk2 siRNA (h2) sc-156139 200 µg/ml $258
Cdk2 (h)-PR sc-29259-PR 10 µM $23
Cdk2 (m)-PR sc-29260-PR 10 µM $23
Cdk2 (h2)-PR sc-156139-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 shRNA Plasmid (h) sc-29259-SH 20 µg $520
Cdk2 shRNA Plasmid (m) sc-29260-SH 20 µg $520
Cdk2 shRNA Plasmid (h2) sc-156139-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 shRNA (h) Lentiviral Particles sc-29259-V 200 µl $625
Cdk2 shRNA (m) Lentiviral Particles sc-29260-V 200 µl $625
Cdk2 shRNA (h2) Lentiviral Particles sc-156139-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAMALWA Cell Lysate sc-2234 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
HeLa + nocodazole Cell Lysate sc-2274 500 µg/200 µl $104
SK-BR-3 Cell Lysate sc-2218 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Cdk2 (m): 293T Lysate sc-119146 100µg/200µl $205
Cdk2 (h2): 293T Lysate sc-172351 100µg/200µl $205

Cdk2 Background Information
In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.

Cdk2 (D-12) Product Citations
See how others have used Cdk2 (D-12): sc-6248 antibody and or Cdk2 (D-12) antibody conjugates.


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Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
 
Cdk2 (D-12)
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sc-6248
Cdk2 (D-12): sc-6248. Western blot analysis of Cdk2 expression in K-562 (A), A-431 (B) and NAMALWA (C) whole cell lysates.
sc-6248
Cdk2 (D-12): sc-6248. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
sc-6248
Cdk2 (D-12): sc-6248. Western blot analysis of Cdk2 expression in untreated (A) and Nocodazale-treated (B) HeLa whole cell lysates.
sc-6248
Western blot analysis of Cdk2 phosphorylation in HeLa (A,D), nocodazole-treated HeLa (B,E) and serum starved HeLa (C,F) whole cell lysates. Antibodies tested include phospho-specific antibody, p-Cdk2 (Thr14/Tyr15)-R: sc-28435-R (A,B,C) and control antibody, Cdk2 (D-12): sc-6248 (D,E,F).
sc-6248
cCdk2 (D-12): sc-6248. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization using indirect FITC (A) staining and direct Alexa Fluor 488 (B) staining.
sc-6248
Cdk2 (D-12): sc-6248. Western blot analysis of Cdk2 expression in HeLa (A) and nocodozole-treated HeLa (B) whole cell lysates.
sc-6248
Cdk2 (D-12): sc-6248. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and mouse Cdk2 transfected: sc-119146 (B) 293T whole cell lysates.
sc-6248
Cdk2 (D-12): sc-6248. Western blot analysis of Cdk2 expression in non-transfected 293T: sc-117752 (A), human Cdk2 transfected 293T: sc-172351 (B) and NAMALWA (C) whole cell lysates.
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