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Bax Antibody (Δ 21): sc-6236

 |  Datasheet

(Based on data analysis)

  • Bax Antibody (Δ 21) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1-171 representing all but the C-terminal 21 amino acids of Baxα of mouse origin
  • recommended for detection of Baxα and Baxβ of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine, bovine and porcine
  • See 54 citations for Bax Antibody (Δ 21)
 
Full-length Bax protein sequence with immunogen highlighted:
MDGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSECLRRIGDELDSNMELQRMIADVDTDSPREVFFRVAADMFADGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGTPTWTVTIFVAGVLTASLTIWKKMG

See additional Bax Antibodies including Bax and Bax beta.

Also see Bax Activators for functional analysis of cellular responses to Bax.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Bax Antibody (Δ 21) sc-6236 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Bax siRNA (h) sc-29212 10 µM $258
Bax siRNA (m) sc-29213 10 µM $258
Bax siRNA (h2) sc-44199 10 µM $258
Bax (h)-PR sc-29212-PR 10 µM, 20 µl $23
Bax (m)-PR sc-29213-PR 10 µM, 20 µl $23
Bax (h2)-PR sc-44199-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Bax shRNA Plasmid (h) sc-29212-SH 20 µg $520
Bax shRNA Plasmid (m) sc-29213-SH 20 µg $520
Bax shRNA Plasmid (h2) sc-44199-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Bax shRNA (h) Lentiviral Particles sc-29212-V 200 µl $625
Bax shRNA (m) Lentiviral Particles sc-29213-V 200 µl $625
Bax shRNA (h2) Lentiviral Particles sc-44199-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CTLL-2 Cell Lysate sc-2242 500 µg/200 µl $104
Bax (m): 293T Lysate sc-126476 100 µg/200 µl $205
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
COLO 320DM Cell Lysate sc-2226 500 µg/200 µl $104
HuT 78 Whole Cell Lysate sc-2208 500 µg/200 µl $104
CCRF-CEM Cell Lysate sc-2225 500 µg/200 µl $104
Ramos Cell Lysate sc-2216 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human BAX 581 19q13.33 NM_004324, NM_138761, NM_138763, NM_138764, NM_138765 Q07812
600040
Mouse Bax 12028 7 B4 Q07813
N/A
 


The Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 is localized to outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. A related protein, designated Bax (Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activity of Bcl-2.

Bax Antibody (Δ 21) Product Citations
See how others have used Bax Antibody (Δ 21) and or Bax Antibody (Δ 21) conjugates.


54 total citations
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Bax Antibody (Δ 21) Data
Click on image to enlarge
Bax (Δ 21): sc-6236. Western blot analysis of Bax expression in RAW 264.7 whole cell lysate.
Bax (Δ 21): sc-6236. Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing cytoplasmic localization.
Bax (Δ 21): sc-6236. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing cytoplasmic staining of smooth muscle cells.
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