epitope mapping at the C-terminus of TRAF5 of mouse origin
recommended for detection of TRAF5 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
TRAF5 Background Information TRAF5 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. TRAF5 is one of the components of a complex associated with the CD40 cytoplasmic domain, which mediates TNF induced NF-kappa B activation and protection from cell death. TRAF5 influences signaling events by other receptors including CD27, CD30, and lymphotoxin-beta receptor. TRAF5 plays a role in osteoclastogenesis. Two alternatively spliced transcript variants encoding the same protein have been reported. The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine-rich extracellular domains.
TRAF5 (C-19) Product Citations
See how others have used TRAF5 (C-19): sc-6195 antibody and or TRAF5 (C-19) antibody conjugates.
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TRAF5 (C-19)
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TRAF5 (C-19): sc-6195. Western blot analysis of TRAF5 expression in CCRF-HSB-2 whole cell lysate.
TRAF5 (C-19): sc-6195. Western blot analysis of TRAF5 expression in non-transfected: sc-117752 (A) and mouse TRAF5 transfected: sc-124243 (B) 293T whole cell lysates.
