 |
- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the C-terminus of GFAP of human origin
- recommended for detection of GFAP of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-6170 P
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
GFAP |
2670 |
17q21.31 |
NM_002055 |
P14136
|
203450 |
| Mouse |
Gfap |
14580 |
11 E1 |
|
P03995
|
N/A |
| |
GFAP Background Information
Glial fibrillary acidic protein, or GFAP, is an intermediate filament (IF) protein belonging to the type III subclass of IF proteins. Like other IF proteins, GFAP is composed of an amino-terminal head domain, a central rod domain and a carboxy-terminal tail domain. GFAP is specifically found in astroglia, a cell type which is highly responsive to neurologic insults. Astrogliosis is found to be a result of mechanical trauma, AIDS dementia, prion infection and inflammatory demylination diseases, and is accompanied by an increase in GFAP expression. GFAP is an immunohistochemical marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system.
| GFAP (C-19) Product Citations |
See how others have used GFAP (C-19): sc-6170 antibody and or GFAP (C-19) antibody conjugates.
36 total citations Loading citations.
|
| |
|
|
|
GFAP (C-19)
Click on image to enlarge
|
GFAP (C-19): sc-6170. Western blot analysis of GFAP expression in non-transfected: sc-110760 (A) and human GFAP transfected: sc-111038 (B) 293 whole cell lysates. GFAP (C-19): sc-6170. Immunofluorescence staining of formalin-fixed cerebellar cell primary culture showing staining of astrocyte processes and cell bodies. Kindly provided by Robert B. Denman, PhD. New York State Institute for Basic Research in Developmental Disabilities.
GFAP (C-19): sc-6170. Western blot analysis of GFAP expression in non-transfected: sc-117752 (A) and human GFAP transfected: sc-115582 (B) 293T whole cell lysates. GFAP (C-19): sc-6170. Western blot analysis of GFAP expression in rat brain tissue extract.
|
|
Download
|
|
