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ZPR1 (N-19) Antibody: sc-6141

 |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of ZPR1 of mouse origin
  • recommended for detection of ZPR1 of mouse and rat origin by WB, IP, IF and ELISA
  • blocking peptide, sc-6141 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6141 X, 200 µg/0.1 ml
 
Additional ZPR1 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Zfp259 22687 9 A5.2 Q62384
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
ZPR1 (N-19) sc-6141 200 µg/ml $279
ZPR1 (N-19) P sc-6141 P
(peptide)
100 µg/0.5 ml $61
ZPR1 (N-19) X sc-6141 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ZPR1 siRNA (m) sc-35283 10 µM $258
ZPR1 (m)-PR sc-35283-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ZPR1 shRNA Plasmid (m) sc-35283-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ZPR1 shRNA (m) Lentiviral Particles sc-35283-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
ZPR1 (m): 293T Lysate sc-124831 100µg/200µl $205

ZPR1 Background Information
Epidermal growth factor (EGF) mediates its growth-promoting effects through its interaction with a cell surface glycoprotein designated the epidermal growth factor receptor (EGFR). Binding of epidermal growth factor to its cognate receptor activates a tyrosine kinase activity, intrinsic to the EGF receptor. ZPR1 is a zinc finger-containing protein that is capable of binding to the intracellular tyrosine kinase domain of the epidermal growth factor receptor. Stimulation of mammalian cells with epidermal growth factor reduces ZPR1 affinity for the EGFR and leads to an accumulation of the protein in the nucleus. The ZPR1 zinc finger is necessary for its association with the EGFR.

ZPR1 (N-19)
Click on image to enlarge
ZPR1 (N-19): sc-6141. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic staining.
ZPR1 (N-19): sc-6141. Western blot analysis of ZPR1 expression in NIH/3T3 whole cell lysate.
ZPR1 (N-19): sc-6141. Western blot analysis of ZPR1 expression in NIH/3T3 whole cell lysate.
ZPR1 (N-19): sc-6141. Western blot analysis of ZPR1 expression in non-transfected: sc-117752 (A) and mouse ZPR1 transfected: sc-124831 (B) 293T whole cell lysates.
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