 |
- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of Trio of human origin
- recommended for detection of Trio of human origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-6060 P
- phycoerythrin conjugate for intracellular FCM, sc-6060 PE, 100 tests
- Alexa Fluor® 405 (sc-6060 AF405), Alexa Fluor® 488 (sc-6060 AF488) and Alexa Fluor® 647 (sc-6060 AF647) conjugates for FCM or immunofluorescence; 100 µg/2 ml
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
| |
| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
TRIO |
7204 |
5p15.2 |
NM_007118 |
O75962
|
601893 |
| |
Trio Background Information
Protein tyrosine phosphatases, or PTPs, are type I transmembrane proteins, membrane-associated proteins or proteins localized in nuclei. Examples of transmembrane PTPs are LAR, PTPa, PTPb, PTPg, PTPd, PTPe, PTPz, PTPk and PTPm. Transmembrane PTPs play diverse roles during development and in adult tissues. Immunodepletion studies have suggested LAR to be a regulator of insulin receptor phosphorylation. Trio is a LAR-interacting protein that contains two functional guanine nuclear exchange factor (GEF) domains and a serine/threonine protein kinase (PSK) domain. One of the the Trio-GEF domains exhibits Rac-specific GEF activity while the other exibits Rho-specific GEF activity. The carboxy terminal PSK domain is most similar to the PSK domains of the CaMK family.
| Trio (D-20) Product Citations |
See how others have used Trio (D-20): sc-6060 antibody and or Trio (D-20) antibody conjugates.
6 total citations Loading citations.
|
| |
| Alexa Fluor® is a
trademark of Molecular Probes Inc., OR., USA |
|
| |
|
|
|
Trio (D-20)
Click on image to enlarge
|
|
Trio (D-20): sc-6060. Western blot analysis of Trio expression in WI-38 (A) and HeLa (B) whole cell lysates.
Trio (D-20) PE: sc-6060 PE. Intracellular FCM analysis of methanol permeabilized HeLa cells. Solid black line histogram represents control goat IgG.
Trio (D-20) PE: sc-6060 PE. Intracellular FCM analysis of fixed and permeabilized HeLa cells. Black line histogram represents the isotype control, normal goat IgG: sc-3992. Trio (D-20) Alexa Fluor 488: sc-6060 AF488. Intracellular FCM analysis of fixed and permeabilized HeLa cells. Black line histogram represents the isotype control, normal goat IgG: sc-45067. Trio (D-20) Alexa Fluor 647: sc-6060 AF647. Intracellular FCM analysis of fixed and permeabilized HeLa cells. Black line histogram represents the isotype control, normal goat IgG: sc-45066. |
|
Download
|
|
