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home » Signaling Intermediates » IFI Antibody / IFI Antibodies » IFI-16 (C-18): sc-6050

IFI-16 (C-18) Antibody: sc-6050

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of IFI-16 of human origin
  • recommended for detection of IFI-16 of human origin by WB, IP, IF, IHC(P), ELISA and indirect FCM using FITC-conjugated donkey anti-goat IgG: sc-2024
  • blocking peptide, sc-6050 P
 
Additional IFI Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   FCM   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human IFI16 3428 1q23.1 NM_005531 Q16666
 147586
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
IFI-16 (C-18) sc-6050 200 µg/ml $279
IFI-16 (C-18) P sc-6050 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IFI-16 siRNA (h) sc-35633 10 µM $258
IFI-16 (h)-PR sc-35633-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IFI-16 shRNA Plasmid (h) sc-35633-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
IFI-16 shRNA (h) Lentiviral Particles sc-35633-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Jurkat nuclear extract sc-2132 1000 µg $143
BJAB Whole Cell Lysate sc-2207 500 µg/200 µl $104
IFI-16 (h): 293 Lysate sc-113241 100µg/200µl $205

IFI-16 Background Information
Interferon-inducible proteins include IFI-202, IFI-203, IFI-204 and D3, and are encoded by six or more structurally related and IFN-inducible mouse genes mapping at the q21-q23 region of chromosome 1. The proteins encoded by these genes have homologous 200 amino acid segments. IFI-202 is a primarily nuclear phosphoprotein which inhibits cell growth, in part by modulating transcriptional activity of NFkB, E2F, AP-1 and p53. Two related human proteins, MNDA (myeloid cell nuclear differentiation antigen) and IFI-16, have also been described. Expression of MNDA has been observed specifically in cells of the granulocyte-macrophage lineage. IFI-16 is constitutively expressed in various T and B cell lines and can be induced by IFN-g in HL-60 cells. At least four of the gene-200 cluster of IFN-inducible proteins, IFI-202, IFI-204, MNDA and IFI-16, are localized in the nucleus.
IFI-16 (C-18)
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sc-6050
IFI-16 (C-18): sc-6050. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lymphoma (A) and immunofluorescence staining of methanol-fixed Jurkat cells (B) showing nuclear staining.
sc-6050
IFI-16 (C-18): sc-6050. Western blot analysis of IFI-16 expression in Jurkat nuclear extract.
sc-6050
IFI-16 (C-18): sc-6050. Indirect, intracellular FCM analysis of fixed and permeabilized Jurkat cells stained with IFI-16 (C-18), followed by FITC-conjugated donkey anti-goat IgG: sc-2024. Black line histogram represents the isotype control, normal goat IgG: sc-3887.
sc-6050
IFI-16 (C-18): sc-6050. Western blot analysis of IFI-16 expression in non-transfected: sc-110760 (A) and human IFI-16 transfected: sc-113241 (B) whole cell lysates.
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