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home » Transcription Regulators » Smad Antibody / Smad Antibodies » Smad2/3 (N-19): sc-6032

Smad2/3 (N-19) Antibody: sc-6032

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of Smad2 of human origin
  • recommended for detection of Smad2 and Smad3 of mouse, rat, human, and, to a lesser extent, mink origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-6032 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6032 X, 200 µg/0.1 ml
 
Additional Smad Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SMAD2 4087 18q21.1 NM_001003652, NM_005901 Q15796
 601366
Human SMAD3 4088 15q22.33 NM_005902 P84022
 603109
Mouse Smad2 17126 18 E3 Q62432
 N/A
Mouse Smad3 17127 9 C Q8BUN5
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Smad2/3 (N-19) sc-6032 200 µg/ml $279
Smad2/3 (N-19) P sc-6032 P
(peptide)
 100 µg/0.5 ml $61
Smad2/3 (N-19) X sc-6032 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Smad2/3 siRNA (h) sc-37238 10 µM $258
Smad2/3 siRNA (m) sc-37239 10 µM $258
Smad2/3 (h)-PR sc-37238-PR 10 µM, 20 µl $23
Smad2/3 (m)-PR sc-37239-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Smad2/3 shRNA Plasmid (h) sc-37238-SH 20 µg $520
Smad2/3 shRNA Plasmid (m) sc-37239-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Smad2/3 shRNA (h) Lentiviral Particles sc-37238-V 200 µl $625
Smad2/3 shRNA (m) Lentiviral Particles sc-37239-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
U-937 Cell Lysate sc-2239 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Smad2 (m): 293T Lysate sc-123638 100µg/200µl $205
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
Smad2 (h2): 293T Lysate sc-114131 100µg/200µl $205
Smad3 (h): 293T Lysate sc-116400 100µg/200µl $205
Smad2 (h): 293T Lysate sc-113452 100µg/200µl $205

Smad2/3 Background Information
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGF∫/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF∫ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGF∫ signaling by interfering with TGF∫-mediated phosphorylation of other Smad proteins.

Smad2/3 (N-19) Product Citations
See how others have used Smad2/3 (N-19): sc-6032 antibody and or Smad2/3 (N-19) antibody conjugates.


35 total citations
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Smad2/3 (N-19)
Click on image to enlarge
sc-6032
Smad2/3 (N-19): sc-6032. Western blot analysis of Smad2/3 expression in C2C12 (A), Mv 1 Lu (B) and U-937 (C) whole cell lysates.
sc-6032
Smad2/3 (N-19): sc-6032. Western blot analysis of Smad2 expression in non-transfected: sc-117752 (A) and human Smad2 transfected: sc-113452 (B) 293T whole cell lysates.
sc-6032
Smad2/3 (N-19): sc-6032. Western blot analysis of Smad3 expression in non-transfected: sc-117752 (A) and human Smad3 transfected: sc-116400 (B) 293T whole cell lysates.
sc-6032
Smad2/3 (N-19): sc-6032. Western blot analysis of Smad2 expression in non-transfected: sc-117752 (A) and human Smad2 transfected: sc-114131 (B) 293T whole cell lysates.
sc-6032
Smad2/3 (N-19): sc-6032. Western blot analysis of Smad2 expression in non-transfected: sc-117752 (A) and mouse Smad2 transfected: sc-123638 (B) 293T whole cell lysates.
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