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home » Transcription Regulators » Smad Antibody / Smad Antibodies » Smad1/5/8 (N-18)-R: sc-6031-R

Smad1/5/8 (N-18)-R Antibody: sc-6031-R

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope mapping at the N-terminus of Smad1 of human origin
  • recommended for detection of Smad1, Smad5 and Smad8 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-6031 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6031 X, 200 µg/0.1 ml
 
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Ordering InformationProduct Citations
Recommended Support Products:
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WB   IP   IF   Gel Shift   ChIP  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Smad1/5/8 (N-18) P sc-6031 P
(peptide)
 100 µg/0.5 ml $61
Smad1/5/8 (N-18) X sc-6031 X 200 µg/0.1 ml $279
Smad1/5/8 (N-18)-R sc-6031-R 200 µg/ml $279
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
ZR-75-1 Cell Lysate sc-2241 500 µg/200 µl $104
SK-N-MC nuclear extract sc-2154 1000 µg $143
NIH/3T3 + PMA nuclear extract sc-2125 1000 µg $143

Smad1/5/8 Background Information
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGF∫/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF∫ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF∫ signaling by interfering with TGF∫-mediated phosphorylation of other Smad family members.

Smad1/5/8 (N-18)-R Product Citations
See how others have used Smad1/5/8 (N-18)-R: sc-6031-R antibody and or Smad1/5/8 (N-18)-R antibody conjugates.


5 total citations
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Smad1/5/8 (N-18)-R
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sc-6031-R
Smad1/5/8 (N-18): sc-6031. Western blot analysis of Smad1/5/8 expression in NIH/3T3 whole cell lysate.
sc-6031-R
Smad1/5/8 (N-18): sc-6031. Western blot analysis of Smad1, Smad5 and Smad 8 expression in SK-N-MC (A) and NIH/3T3 (B) nuclear extracts.
sc-6031-R
Smad1/5/8 (N-18): sc-6031. Western blot analysis of Smad expression in Hep G2 (A) and ZR-75-1 (B) whole cell lysates.
sc-6031-R
Smad1/5/8 (N-18)-R: sc-6031-R. Western blot analysis of Smad1/5/8 expression in DU 145 (A), HeLa (B), PC-3 (C) and SK-N-MC (D) nuclear extracts.
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