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home » Transcription Regulators » Smad Antibody / Smad Antibodies » Smad (C-17): sc-6030

Smad (C-17) Antibody: sc-6030

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping at the C-terminus of Smad of human origin
  • recommended for detection of Smad1, Smad2, Smad3, Smad5 and Smad8 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-6030 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-6030 X, 200 µg/0.1 ml
 
Additional Smad Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   Gel Shift   ChIP  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SMAD1 4086 4q31.22 NM_001003688, NM_005900 Q15797
 601595
Human SMAD2 4087 18q21.1 NM_001003652, NM_005901 Q15796
 601366
Human SMAD3 4088 15q22.33 NM_005902 P84022
 603109
Human SMAD5 4090 5q31.2 NM_001001419, NM_001001420, NM_005903 Q99717
 603110
Human SMAD9 4093 13q13.3 NM_005905 O15198
 603295
Mouse Smad1 17125 8 C2 P70340
 N/A
Mouse Smad2 17126 18 E3 Q62432
 N/A
Mouse Smad3 17127 9 C Q8BUN5
 N/A
Mouse Smad5 17129 13 B1 P97454
 N/A
Mouse Smad9 55994 3 C Q9JIW5
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Smad (C-17) sc-6030 200 µg/ml $279
Smad (C-17) P sc-6030 P
(peptide)
 100 µg/0.5 ml $61
Smad (C-17) X sc-6030 X 200 µg/0.1 ml $279
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
ZR-75-1 Cell Lysate sc-2241 500 µg/200 µl $104
Smad2 (h): 293T Lysate sc-113452 100µg/200µl $205
Smad3 (h): 293T Lysate sc-116400 100µg/200µl $205
Smad2 (h2): 293T Lysate sc-114131 100µg/200µl $205
Smad2 (m): 293T Lysate sc-123638 100µg/200µl $205

Smad Background Information
Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGF∫/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF∫ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF∫ signaling by interfering with TGF∫-mediated phosphorylation of other Smad family members.

Smad (C-17) Product Citations
See how others have used Smad (C-17): sc-6030 antibody and or Smad (C-17) antibody conjugates.


1 total citations
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Smad (C-17)
Click on image to enlarge
sc-6030
Smad (C-17): sc-6030. Western blot analysis of Smad2 expression in non-transfected: sc-117752 (A) and human Smad2 transfected: sc-113452 (B) 293T whole cell lysates.
sc-6030
Smad (C-17): sc-6030. Western blot analysis of Smad3 expression in non-transfected: sc-117752 (A) and human Smad3 transfected: sc-116400 (B) 293T whole cell lysates.
sc-6030
Smad (C-17): sc-6030. Western blot analysis of Smad2 expression in non-transfected: sc-117752 (A) and human Smad2 transfected: sc-114131 (B) 293T whole cell lysates.
sc-6030
Smad (C-17): sc-6030. Western blot analysis of Smad2 expression in non-transfected: sc-117752 (A) and mouse Smad2 transfected: sc-123638 (B) 293T whole cell lysates.
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