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β-catenin Antibody (12F7): sc-59737

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  • β-catenin Antibody (12F7) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against a recombinant β-catenin of human origin
  • recommended for detection of β-catenin of mouse, rat and human origin by WB, IP, IF and IHC(P)
  • See 10 citations for β-catenin Antibody (12F7)
 

See additional Catenin Antibodies including Catenin, alpha E-catenin, alpha N-catenin, alpha T-catenin , beta-catenin, delta-catenin and gamma-catenin.

Also see chemical beta-catenin Inhibitors for functional analysis of cellular responses to beta-catenin.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin Antibody (12F7) sc-59737 200 µg/ml $279
 CRISPR KO, HDR and Nickase Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin CRISPR/Cas9 KO Plasmid (h) sc-400038 20 µg $345
β-catenin HDR Plasmid (h) sc-400038-HDR 20 µg $385
β-catenin Double Nickase Plasmid (h) sc-400038-NIC 20 µg $355
β-catenin Double Nickase Plasmid (h2) sc-400038-NIC-2 20 µg $355
β-catenin CRISPR/Cas9 KO Plasmid (m) sc-419477 20 µg $345
β-catenin HDR Plasmid (m) sc-419477-HDR 20 µg $385
β-catenin Double Nickase Plasmid (m) sc-419477-NIC 20 µg $355
β-catenin Double Nickase Plasmid (m2) sc-419477-NIC-2 20 µg $355
 CRISPR Activation Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin CRISPR Activation Plasmid (h) sc-400038-ACT 20 µg $345
β-catenin CRISPR Activation Plasmid (h2) sc-400038-ACT-2 20 µg $345
β-catenin Lentiviral Activation Particles (h) sc-400038-LAC 200 µl $395
β-catenin Lentiviral Activation Particles (h2) sc-400038-LAC-2 200 µl $395
β-catenin CRISPR Activation Plasmid (m) sc-419477-ACT 20 µg $345
β-catenin CRISPR Activation Plasmid (m2) sc-419477-ACT-2 20 µg $345
β-catenin Lentiviral Activation Particles (m) sc-419477-LAC 200 µl $395
β-catenin Lentiviral Activation Particles (m2) sc-419477-LAC-2 200 µl $395
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin siRNA (h) sc-29209 10 µM $258
β-catenin siRNA (m) sc-29210 10 µM $258
β-catenin siRNA (h2) sc-44252 10 µM $258
β-catenin siRNA (m2) sc-44253 10 µM $258
β-catenin (h)-PR sc-29209-PR 10 µM, 20 µl $23
β-catenin (m)-PR sc-29210-PR 10 µM, 20 µl $23
β-catenin (h2)-PR sc-44252-PR 10 µM, 20 µl $23
β-catenin (m2)-PR sc-44253-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin shRNA Plasmid (h) sc-29209-SH 20 µg $520
β-catenin shRNA Plasmid (m) sc-29210-SH 20 µg $520
β-catenin shRNA Plasmid (h2) sc-44252-SH 20 µg $520
β-catenin shRNA Plasmid (m2) sc-44253-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin shRNA (h) Lentiviral Particles sc-29209-V 200 µl $625
β-catenin shRNA (m) Lentiviral Particles sc-29210-V 200 µl $625
β-catenin shRNA (h2) Lentiviral Particles sc-44252-V 200 µl $625
β-catenin shRNA (m2) Lentiviral Particles sc-44253-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
SK-BR-3 Cell Lysate sc-2218 500 µg/200 µl $104
β-catenin (h): 293T Lysate sc-116622 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CTNNB1 1499 3p22.1 NM_001904 P35222
155255
Mouse Ctnnb1 12387 9 F4 Q02248
N/A
 


The catenins, å, ∫ and ©, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. å-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. ∫-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. ∫-catenin has also been found in complexes with the tumor suppressor protein APC (5). ©-catenin, also known as plakoglobin, binds with å-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPµ associates with catenin/cadherin complexes and may regulate complex signaling.

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β-catenin Antibody (12F7) Product Reviews

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β-catenin Antibody (12F7) Product Citations
See how others have used β-catenin Antibody (12F7) and or β-catenin Antibody (12F7) conjugates.


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β-catenin Antibody (12F7) Data
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β-catenin (12F7): sc-59737. Western blot analysis of β-catenin expression in HeLa whole cell lysate.
β-catenin (12F7): sc-59737. Western blot analysis of β-catenin expression in non-transfected: sc-117752 (A) and human β-catenin transfected: sc-116622 (B) 293T whole cell lysates.
β-catenin (12F7): sc-59737. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.
β-catenin (12F7): sc-59737. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing membrane staining of glandular cells.
β-catenin (12F7): sc-59737. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse colon tissue showing membrane staining of glandular cells and cytoplasmic staining of interstitial cells. Kindly provided by Dr. Jun Hee Lee, Department of Molecular and Integrative Physiology, University of Michigan Geriatric Center.
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