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β-catenin Antibody (12F7): sc-59737

 |  Datasheet

(Based on data analysis)

  • β-catenin Antibody (12F7) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against a recombinant β-catenin of human origin
  • recommended for detection of β-catenin of mouse, rat and human origin by WB, IP, IF and IHC(P)
  • See 10 citations for β-catenin Antibody (12F7)
 

See additional Catenin Antibodies including Catenin, alpha E-catenin, alpha N-catenin, alpha T-catenin , beta-catenin, delta-catenin and gamma-catenin.

Also see chemical beta-catenin Inhibitors for functional analysis of cellular responses to beta-catenin.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin Antibody (12F7) sc-59737 200 µg/ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin CRISPR/Cas9 KO Plasmid (h) sc-400038 20 µg $345
β-catenin HDR Plasmid (h) sc-400038-HDR 20 µg $385
β-catenin CRISPR/Cas9 KO Plasmid (m) sc-419477 20 µg $345
β-catenin HDR Plasmid (m) sc-419477-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin siRNA (h) sc-29209 10 µM $258
β-catenin siRNA (m) sc-29210 10 µM $258
β-catenin siRNA (h2) sc-44252 10 µM $258
β-catenin siRNA (m2) sc-44253 10 µM $258
β-catenin (h)-PR sc-29209-PR 10 µM, 20 µl $23
β-catenin (m)-PR sc-29210-PR 10 µM, 20 µl $23
β-catenin (h2)-PR sc-44252-PR 10 µM, 20 µl $23
β-catenin (m2)-PR sc-44253-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin shRNA Plasmid (h) sc-29209-SH 20 µg $520
β-catenin shRNA Plasmid (m) sc-29210-SH 20 µg $520
β-catenin shRNA Plasmid (h2) sc-44252-SH 20 µg $520
β-catenin shRNA Plasmid (m2) sc-44253-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
β-catenin shRNA (h) Lentiviral Particles sc-29209-V 200 µl $625
β-catenin shRNA (m) Lentiviral Particles sc-29210-V 200 µl $625
β-catenin shRNA (h2) Lentiviral Particles sc-44252-V 200 µl $625
β-catenin shRNA (m2) Lentiviral Particles sc-44253-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
SK-BR-3 Cell Lysate sc-2218 500 µg/200 µl $104
β-catenin (h): 293T Lysate sc-116622 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CTNNB1 1499 3p22.1 NM_001904 P35222
155255
Mouse Ctnnb1 12387 9 F4 Q02248
N/A
 


The catenins, å, ∫ and ©, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. å-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. ∫-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. ∫-catenin has also been found in complexes with the tumor suppressor protein APC (5). ©-catenin, also known as plakoglobin, binds with å-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPµ associates with catenin/cadherin complexes and may regulate complex signaling.

β-catenin Antibody (12F7) Product Citations
See how others have used β-catenin Antibody (12F7) and or β-catenin Antibody (12F7) conjugates.


10 total citations
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β-catenin Antibody (12F7) Data
Click on image to enlarge
β-catenin (12F7): sc-59737. Western blot analysis of β-catenin expression in non-transfected: sc-117752 (A) and human β-catenin transfected: sc-116622 (B) 293T whole cell lysates.
β-catenin (12F7): sc-59737. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.
β-catenin (12F7): sc-59737. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing membrane staining of glandular cells.
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