santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Transcription Regulators » CtIP Antibody / CtIP Antibodies » CtIP (K-19): sc-5969

CtIP (K-19) Antibody: sc-5969

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an internal region of CtIP of human origin
  • recommended for detection of CtIP of mouse and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, porcine and avian
  • blocking peptide, sc-5969 P
 
Additional CtIP Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RBBP8 5932 18q11.2 NM_002894, NM_203291, NM_203292 Q99708
 604124
Mouse Rbbp8 225182 18 A1 NM_001081223 NP_001074692
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CtIP (K-19) sc-5969 200 µg/ml $279
CtIP (K-19) P sc-5969 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CtIP siRNA (h) sc-37765 10 µM $258
CtIP siRNA (m) sc-37766 10 µM $258
CtIP (h)-PR sc-37765-PR 10 µM $23
CtIP (m)-PR sc-37766-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CtIP shRNA Plasmid (h) sc-37765-SH 20 µg $520
CtIP shRNA Plasmid (m) sc-37766-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CtIP shRNA (h) Lentiviral Particles sc-37765-V 200 µl $625
CtIP shRNA (m) Lentiviral Particles sc-37766-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
T24 Cell Lysate sc-2292 500 µg/200 µl $104
Jurkat nuclear extract sc-2132 1000 µg $143
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104

CtIP Background Information
CtBP1 is a cellular phosphoprotein that associates with various proteins and functions as a co-repressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a five amino acid motif, PLDLS, to repress E1A-induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of dEF1, a cellular zinc finger-homeodomain protein, and thereby enhance dEF1-induced transcriptional silencing. In addition, CtBP complexes with CtIP, a protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. CtIP/CtBP binding to BRCA1 inhibits the transactivation of the p21 promoter, and it is critical for regulating p21 transcription in response to DNA damage.

CtIP (K-19) Product Citations
See how others have used CtIP (K-19): sc-5969 antibody and or CtIP (K-19) antibody conjugates.


1 total citations
Loading citations.
 
CtIP (K-19)
Click on image to enlarge
sc-5969
CtIP (K-19): sc-5969. Western blot analysis of CtIP expression in non-transfected: sc-117752 (A) and mouse CtIP transfected: sc-119500 (B) 293T whole cell lysates.
Download
Datasheets
Get Adobe Acrobat Reader