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DNA pol ζ Antibody (N-20): sc-5939

 |  Datasheet

(Based on data analysis)

  • DNA pol ζ Antibody (N-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of DNA pol ζ of human origin
  • recommended for DNA pol ζ of mouse, rat and human origin of WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
  • blocking peptide, sc-5939 P
  • See 1 citations for DNA pol ζ Antibody (N-20)
 

See additional DNA Polymerase Antibodies including DNA Polymerase, DNA pol δ 3, DNA pol alpha, DNA pol beta, DNA pol delta cat, DNA pol epsilon, DNA pol epsilon A, DNA pol epsilon B, DNA pol gamma, DNA pol iota, DNA pol lambda, DNA pol mu, DNA pol nu, DNA pol theta, DNA pol zeta, DNA pol delta 2, DNA pol gamma 2, DNA pol delta 4 and DNA pol epsilon 4.

Also see DNA Polymerase Inhibitors for functional analysis of cellular responses to DNA Polymerase.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
DNA pol ζ Antibody (N-20) sc-5939 200 µg/ml $279
DNA pol ζ(N-20) P sc-5939 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DNA pol ζ siRNA (h) sc-37790 10 µM $258
DNA pol ζ (h)-PR sc-37790-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DNA pol ζ shRNA Plasmid (h) sc-37790-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
DNA pol ζ shRNA (h) Lentiviral Particles sc-37790-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
K-562 nuclear extract sc-2130 250 µg/0.05 ml $143
Jurkat nuclear extract sc-2132 250 µg/0.05 ml $143
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human REV3L 5980 6q21 NM_002912 O60673
 602776
Mouse Rev3l 19714 10 B1 Q61493
 N/A
 

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases (1). In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches (2). These exonucleases include the family of DNA polymerases (3). DNA pol å, ∫, ∂, and e are involved in DNA replication and repair (4). DNA pol ∂ and DNA pol e are multisubunit enzymes, with DNA pol ∂ consisting of two subunits p125, which interacts with the sliding DNA clamp protein PCNA, and p50 (5). The nuclear-encoded DNA pol © is the only DNA polymerase required for the replication of the mitochondrial DNA (6). DNA pol Ω is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis (7). DNA pol œ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks (8).

DNA pol ζ Antibody (N-20) Product Citations
See how others have used DNA pol ζ Antibody (N-20) and or DNA pol ζ Antibody (N-20) conjugates.


1 total citations
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DNA pol ζ Antibody (N-20) Data
Click on image to enlarge
sc-5939
Western blot analysis of DNA pol δ cat expression in NIH/3T3 nuclear extract (A) and DNA pol ζ1 expression in K-562 (B) and Jurkat (C) nuclear extracts. Antibodies tested include DNA pol δ cat (C-20): sc-8797 (A) and DNA pol ζ (N-20): sc-5939 (B,C).
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