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Melanoma Marker Antibody (HMB45): sc-59305

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  • Melanoma Marker Antibody (HMB45) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
  • raised against extract of pigmented melanoma metastases from lymph nodes of human origin
  • recommended for detection of a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes in junctional and blue nevus cells of mouse, rat and human origin by WB, IP, IF and IHC(P); non cross-reactive with non-melanocytic cells
  • agarose (sc-59305 AC), 500 µg/0.25 ml agarose in 1 ml, for IP; HRP (sc-59305 HRP), 200 µg/ml, for WB, IHC(P) and ELISA; phycoerythrin (sc-59305 PE), fluorescein (sc-59305 FITC), Alexa Fluor® 488 (sc-59305 AF488) or Alexa Fluor® 647 (sc-59305 AF647), 200 µg/ml, for IF, IHC(P) and FCM
  • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP): sc-516102, our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
  • See 7 citations for Melanoma Marker Antibody (HMB45)
 

See additional Melanoma Marker Antibodies.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Melanoma Marker Antibody (HMB45) sc-59305 200 µg/ml $279
Melanoma Marker Antibody (HMB45) AC sc-59305 AC 500 µg/ml, 25% ag $366
Melanoma Marker Antibody (HMB45) AF488 sc-59305 AF488 200 µg/ml $314
Melanoma Marker Antibody (HMB45) AF647 sc-59305 AF647 200 µg/ml $314
Melanoma Marker Antibody (HMB45) FITC sc-59305 FITC 200 µg/ml $292
Melanoma Marker Antibody (HMB45) HRP sc-59305 HRP 200 µg/ml $279
Melanoma Marker Antibody (HMB45) PE sc-59305 PE 200 µg/ml $303


Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but may also involve other sites. Malignant melanoma underlies the majority of skin cancer-related deaths. Melanoma originates in melanocytes, the cells which produce the pigment melanin, which colors human skin, hair, and eyes and is heavily concentrated in most moles. Epidemiologic studies suggest that exposure to ultraviolet radiation is one of the major contributors to the development of melanoma. The four most common types of melanoma in the skin are superficial spreading melanomas, which evolve from a precursor lesion (usually a dysplastic nevus); nodular melanomas, the most aggressive form; acral lentiginous melanomas, which are seen on the palms, soles and under the nails; and Lentigo malignas, which consist of malignant cells but do not show invasive growth.

Melanoma Marker Antibody (HMB45) Product Reviews

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Melanoma Marker Antibody (HMB45) Product Citations
See how others have used Melanoma Marker Antibody (HMB45) and or Melanoma Marker Antibody (HMB45) conjugates.


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Melanoma Marker Antibody (HMB45) Data
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Melanoma Marker (HMB45): sc-59305. Western blot analysis of Melanoma Marker expression in SK-MEL-28 whole cell lysate.
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