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Melanoma Marker Antibody (HMB45): sc-59305

 |  Datasheet

(Based on data analysis)

  • Melanoma Marker Antibody (HMB45) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against extract of pigmented melanoma metastases from lymph nodes of human origin
  • recommended for detection of a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate of human origin by WB, IP, IF and IHC(P); non cross-reactive with non-melanocytic cells
  • See 2 citations for Melanoma Marker Antibody (HMB45)
 

See additional Melanoma Marker Antibodies.

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Melanoma Marker Antibody (HMB45) sc-59305 200 µg/ml $279
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Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but may also involve other sites. Malignant melanoma underlies the majority of skin cancer-related deaths. Melanoma originates in melanocytes, the cells which produce the pigment melanin, which colors human skin, hair, and eyes and is heavily concentrated in most moles. Epidemiologic studies suggest that exposure to ultraviolet radiation is one of the major contributors to the development of melanoma. The four most common types of melanoma in the skin are superficial spreading melanomas, which evolve from a precursor lesion (usually a dysplastic nevus); nodular melanomas, the most aggressive form; acral lentiginous melanomas, which are seen on the palms, soles and under the nails; and Lentigo malignas, which consist of malignant cells but do not show invasive growth.

Melanoma Marker Antibody (HMB45) Product Citations
See how others have used Melanoma Marker Antibody (HMB45) and or Melanoma Marker Antibody (HMB45) conjugates.


2 total citations
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Melanoma Marker Antibody (HMB45) Data
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Melanoma Marker (HMB45): sc-59305. Western blot analysis of Melanoma Marker expression in SK-MEL-28 whole cell lysate.
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